Morphine sulfate and Zelnorm drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Morphine sulfate (morphine sulfate) and Zelnorm (tegaserod maleate). Common drug interactions include paraesthesia among females and cardio-respiratory arrest among males.

The phase IV clinical study analyzes what interactions people have when they take Morphine sulfate and Zelnorm. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Morphine sulfate?

Morphine sulfate has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 87,261 Morphine sulfate users. Check the latest studies of Morphine sulfate.

What is Zelnorm?

Zelnorm has active ingredients of tegaserod maleate. eHealthMe is studying from 7,261 Zelnorm users. Check the latest studies of Zelnorm.



On Jul, 31, 2026

26 people who take Morphine sulfate and Zelnorm together, and have interactions are studied.

Morphine sulfate and Zelnorm drug interactions.

What are the common drug interactions of Morphine Sulfate and Zelnorm, by gender? *:

female:

  1. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  2. Sinusitis (inflammation of sinus)
  3. Hyperlipidaemia (presence of excess lipids in the blood)
  4. Fatigue (feeling of tiredness)
  5. Headache (pain in head)
  6. Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
  7. Hypertension (high blood pressure)
  8. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  9. Thirst
  10. Abdominal pain

male:

  1. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  2. Hyperhidrosis (abnormally increased sweating)
  3. Loss of consciousness
  4. Nausea (feeling of having an urge to vomit)

What are the common drug interactions of Morphine Sulfate and Zelnorm, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Oedema peripheral (superficial swelling)
  2. Urticaria (rash of round, red welts on the skin that itch intensely)

40-49:

  1. Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
  2. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  3. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  4. Hyperhidrosis (abnormally increased sweating)
  5. Loss of consciousness
  6. Mastoiditis (infection of mastoid bone)
  7. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  8. Pulmonary embolism (blockage of the main artery of the lung)
  9. Injury
  10. Nausea (feeling of having an urge to vomit)

50-59:

  1. Heart rate increased
  2. Carcinoid tumour pulmonary (slow growing tumour)
  3. Cardiac flutter (abnormal heart rhythm)
  4. Confusional state
  5. Disability
  6. Heart rate irregular
  7. Limb discomfort (discomfort in leg)
  8. Lung neoplasm malignant (cancer tumour of lung)
  9. Abdominal pain upper
  10. Abnormal faeces (abnormal stool)

60+:

  1. Drug hypersensitivity
  2. Abdominal discomfort
  3. Fatigue (feeling of tiredness)
  4. Femur fracture
  5. Micturition urgency (urgency to pass the urine)
  6. Rash macular (small, flat red spots)
  7. Sleep disorder due to a general medical condition
  8. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  9. Barrett's oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach)
  10. Bladder disorder

What are the existing conditions these people have? *

  1. Neoplasm Malignant (cancer tumour): 6 people, 23.08%
  2. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 4 people, 15.38%
  3. Irritable Bowel Syndrome: 4 people, 15.38%
  4. High Blood Pressure: 4 people, 15.38%
  5. Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 4 people, 15.38%
  6. Gastric Disorder (disease of stomach): 4 people, 15.38%
  7. Breast Cancer: 4 people, 15.38%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 11.54%
  9. Blood Pressure Abnormal: 3 people, 11.54%
  10. General Physical Health Deterioration (weak health status): 3 people, 11.54%

* Approximation only. Some reports may have incomplete information.

Do you take Morphine sulfate and Zelnorm?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Morphine sulfate and Zelnorm:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Morphine sulfate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Zelnorm:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Morphine sulfate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zelnorm and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on morphine sulfate and tegaserod maleate (the active ingredients of Morphine sulfate and Zelnorm, respectively), and Morphine sulfate and Zelnorm (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: