Motrin and Fluorouracil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Motrin (ibuprofen) and Fluorouracil (fluorouracil). Common drug interactions include gait disturbance among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Motrin and Fluorouracil. It is created by eHealthMe based on reports of 60 people who take the same drugs from the FDA, and is updated regularly.

What is Motrin?

Motrin has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 38,332 Motrin users. Check the latest studies of Motrin.

What is Fluorouracil?

Fluorouracil has active ingredients of fluorouracil. It is often used in colon cancer metastatic. eHealthMe is studying from 97,087 Fluorouracil users. Check the latest studies of Fluorouracil.

On Jul, 12, 2026

60 people who take Motrin and Fluorouracil together, and have interactions are studied.

Motrin and Fluorouracil drug interactions.

What are the common drug interactions of Motrin and Fluorouracil, by gender? *:

female:

Gait disturbance
Nausea (feeling of having an urge to vomit)
Dyspepsia (indigestion)
Dehydration (dryness resulting from the removal of water)
Dyspnoea (difficult or laboured respiration)
Osteonecrosis of jaw (death of bone of jaw)
Alanine aminotransferase increased
Anaemia (lack of blood)
Ascites (accumulation of fluid in the abdominal cavity)
Back pain

male:

Asthenia (weakness)
Abdominal distension
Blood pressure decreased
Bone neoplasm (tumour of bone)
Bronchiolitis (inflammation of the membranes lining the bronchioles in lungs)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac hypertrophy (thickening of the heart muscle)
Cerumen impaction
Colour blindness (inability to view some colour)
Conjunctivitis (pink eye)

What are the common drug interactions of Motrin and Fluorouracil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Abdominal distension
Abdominal pain upper
Adenoiditis (inflammation of an abnormally enlarged mass of lymphoid tissue at the back of the pharynx)
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Alopecia (absence of hair from areas of the body)
Alpha 1 foetoprotein increased
Anaemia (lack of blood)
Arthralgia (joint pain)
Asthenia (weakness)
Astigmatism (refractive error of the eye in which parallel rays of light from an external source do not converge on a single focal point on the retina)

10-19:

n/a

20-29:

n/a

30-39:

Abdominal pain
Abortion spontaneous (naturally occurring miscarriage)
Colitis (inflammation of colon)
Pregnancy

40-49:

Abdominal pain
Pain in extremity
Cough
Dyspnoea (difficult or laboured respiration)
Pleural effusion (water on the lungs)
Aspartate aminotransferase increased
Asthenia (weakness)
Atelectasis (partial or complete collapse of the lung)
Blood alkaline phosphatase increased
Blood bilirubin increased

50-59:

Activities of daily living impaired
Altered visual depth perception
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bacterial test positive
Blood calcium increased
Bone disorder
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Carcinoembryonic antigen increased

60+:

Anxiety
Metastases to lung (cancer spreads to lung)
Decreased interest
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Deformity (disfigurement)
Discomfort
Dizziness
Dyspepsia (indigestion)
Emotional distress
Gait disturbance

What are the existing conditions these people have? *

Breast Cancer: 9 people, 15.00%
Stress And Anxiety: 8 people, 13.33%
Reflux Gastritis (a condition in which the lining of a person's stomach becomes inflamed as a result of exposure to bile): 8 people, 13.33%
Immunodeficiency Common Variable: 5 people, 8.33%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 5 people, 8.33%
Breast Cancer Metastatic: 5 people, 8.33%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 5.00%
Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 3 people, 5.00%
Colon Cancer: 3 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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