Motrin and Robinul drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Motrin (ibuprofen) and Robinul (glycopyrrolate). Common drug interactions include venous insufficiency among females and duodenal ulcer among males.
The phase IV clinical study analyzes what interactions people have when they take Motrin and Robinul. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.
What is Motrin?
Motrin has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 38,332 Motrin users. Check the latest studies of Motrin.
What is Robinul?
Robinul has active ingredients of glycopyrrolate. It is often used in hyperhidrosis. eHealthMe is studying from 1,663 Robinul users. Check the latest studies of Robinul.
27 people who take Motrin and Robinul together, and have interactions are studied.

What are the common drug interactions of Motrin and Robinul, by gender? *:
female:
- Venous insufficiency (poor circulation of blood caused by damaged or enlarged veins)
- Vertigo
- Chronic respiratory failure
- Hepatitis c virus test positive
- Parainfluenzae virus infection
- Pneumonia bacterial (pneumonia associated with bacterial infection)
- Breast cancer
- Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
- Death
- Gallbladder injury
male:
- Duodenal ulcer
- Haemoglobin decreased
- Cough
- Death
- Depressed level of consciousness
- Discomfort
- Drug ineffective
- Drug maladministration
- Ear infection
- Fatigue (feeling of tiredness)
What are the common drug interactions of Motrin and Robinul, by age (0-1 to 60+)? *:
0-1:
- Chronic respiratory failure
- Parainfluenzae virus infection
- Pneumonia bacterial (pneumonia associated with bacterial infection)
2-9:
- Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
- Death
- Influenza
10-19:
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Urine output decreased
- Viral infection
- Vomiting
- Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
- Duodenal ulcer
- Haemoglobin decreased
- Melaena (the passage of black, tarry stools)
- Abdominal distension
- Abnormal behaviour
20-29:
n/a
30-39:
- Hepatitis c virus test positive
40-49:
- Abdominal distension
- Abdominal pain
- Device dislocation
- Dysmenorrhoea (painful menstruation)
- Fatigue (feeling of tiredness)
- Lymphocyte count decreased
- Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)
- Migraine (headache)
- Uterine haemorrhage (uterine bleeding)
- Dyspnoea (difficult or laboured respiration)
50-59:
- Breast calcifications (deposits of calcium that can be seen on a mammogram of the breast)
- Breast cancer in situ
- Breast mass
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Burning sensation
- Carotid bruit (sound heard over the carotid artery area during auscultation)
- Chest pain
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Colonic polyp (extra part of colon tissue grow in intestine)
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
60+:
- Cholecystitis chronic (long lasting infection of gallbladder)
- Drug ineffective
- Drug maladministration
- Injury
- Muscle twitching
- Surgery prolonged
What are the existing conditions these people have? *
- Birth Control: 4 people, 14.81%
- Depression: 4 people, 14.81%
- Nausea (feeling of having an urge to vomit): 3 people, 11.11%
- Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 3 people, 11.11%
- Migraine Without Aura (headache without neurological problems): 3 people, 11.11%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 11.11%
- Nausea And Vomiting: 2 people, 7.41%
- Osteoporosis (bones weak and more likely to break): 2 people, 7.41%
- Urticaria (rash of round, red welts on the skin that itch intensely): 2 people, 7.41%
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 7.41%
* Approximation only. Some reports may have incomplete information.
Do you take Motrin and Robinul?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Motrin and Robinul:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Motrin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Robinul:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Motrin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Robinul and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
- D'souza S, Gowler V, "Glycopyrrolate‐induced respiratory arrest: an unusual side effect", Acta Anaesthesiologica Scandinavica, 2015 Mar .
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
- D'souza S, Gowler V, "Glycopyrrolate‐induced respiratory arrest: an unusual side effect", Acta Anaesthesiologica Scandinavica, 2015 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on ibuprofen and glycopyrrolate (the active ingredients of Motrin and Robinul, respectively), and Motrin and Robinul (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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