Motrin and Tequin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Motrin (ibuprofen) and Tequin (gatifloxacin). Common drug interactions include arthralgia among females and benign prostatic hyperplasia among males.

The phase IV clinical study analyzes what interactions people have when they take Motrin and Tequin. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Motrin?

Motrin has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 38,332 Motrin users. Check the latest studies of Motrin.

What is Tequin?

Tequin has active ingredients of gatifloxacin. eHealthMe is studying from 4,645 Tequin users. Check the latest studies of Tequin.



On Jul, 17, 2026

31 people who take Motrin and Tequin together, and have interactions are studied.

Motrin and Tequin drug interactions.

What are the common drug interactions of Motrin and Tequin, by gender? *:

female:

  1. Arthralgia (joint pain)
  2. Bone disorder
  3. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  4. Diabetic hyperosmolar non ketoacidosis (extremely high blood sugar (glucose) levels without ketone bodies in blood)
  5. Diarrhoea
  6. Dizziness
  7. Dyspnoea (difficult or laboured respiration)
  8. Femoral neck fracture (neck of femur bone fracture)
  9. Femur fracture
  10. Fracture displacement

male:

  1. Benign prostatic hyperplasia (benign enlargement of the prostate)
  2. Hypertension (high blood pressure)
  3. Blood bilirubin increased
  4. Blood calcium decreased
  5. Bone disorder
  6. Colonic polyp (extra part of colon tissue grow in intestine)
  7. Confusional state
  8. Death
  9. Dehydration (dryness resulting from the removal of water)
  10. Delirium (wild excitement)

What are the common drug interactions of Motrin and Tequin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Bruxism (habitual grinding of the teeth, typically during sleep)
  2. Trismus (reduced opening of the jaws)

30-39:

  1. Antepartum haemorrhage (bleeding from the vagina during pregnancy from the 24th week)
  2. Back pain
  3. Breast cyst
  4. Budd-chiari syndrome (problem that results from blood clotting in the veins flowing out of the liver (hepatic veins))
  5. Cholecystitis (infection of gallbladder)
  6. Cholecystitis chronic (long lasting infection of gallbladder)
  7. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  8. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  9. Gallbladder injury
  10. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

40-49:

n/a

50-59:

  1. Constipation
  2. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  3. Dyspepsia (indigestion)
  4. Hallucination (an experience involving the perception of something not present)
  5. Herpes zoster
  6. Hypertension (high blood pressure)
  7. Pulmonary embolism (blockage of the main artery of the lung)
  8. Abdominal pain
  9. Abscess oral (abscess in the mouth)
  10. Anxiety

60+:

  1. Fall
  2. Anxiety
  3. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  4. Asthenia (weakness)
  5. Benign prostatic hyperplasia (benign enlargement of the prostate)
  6. Beta globulin increased
  7. Blood bilirubin increased
  8. Blood calcium decreased
  9. Colonic polyp (extra part of colon tissue grow in intestine)
  10. Confusional state

What are the existing conditions these people have? *

  1. Painful Respiration: 2 people, 6.45%
  2. Osteoporosis (bones weak and more likely to break): 2 people, 6.45%
  3. Lung Cancer - Non-Small Cell (lung cancer): 2 people, 6.45%
  4. Bone Pain: 2 people, 6.45%
  5. Allergic Sinusitis: 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Motrin and Tequin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Motrin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Tequin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Motrin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tequin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen and gatifloxacin (the active ingredients of Motrin and Tequin, respectively), and Motrin and Tequin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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