Motrin and Valcyte drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Motrin (ibuprofen) and Valcyte (valganciclovir hydrochloride). Common drug interactions include gastrointestinal haemorrhage among females and bronchiolitis among males.

The phase IV clinical study analyzes what interactions people have when they take Motrin and Valcyte. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Motrin?

Motrin has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 38,332 Motrin users. Check the latest studies of Motrin.

What is Valcyte?

Valcyte has active ingredients of valganciclovir hydrochloride. It is often used in cmv - immunocompromised host. eHealthMe is studying from 6,409 Valcyte users. Check the latest studies of Valcyte.



On Jul, 29, 2026

13 people who take Motrin and Valcyte together, and have interactions are studied.

Motrin and Valcyte drug interactions.

What are the common drug interactions of Motrin and Valcyte, by gender? *:

female:

  1. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  2. Activated partial thromboplastin time prolonged
  3. Blood fibrinogen decreased
  4. Blood pressure inadequately controlled
  5. Cardiac arrest
  6. Coagulopathy (blood's ability to clot is impaired)
  7. Colitis (inflammation of colon)
  8. Cytomegalovirus test positive
  9. Hepatic failure (liver failure)
  10. Infective glossitis (tongue can become inflamed or infected)

male:

  1. Bronchiolitis (inflammation of the membranes lining the bronchioles in lungs)
  2. Chronic kidney disease
  3. Tricuspid valve incompetence (inefficient heart valve)
  4. Upper respiratory tract infection
  5. Viral infection
  6. Anaemia (lack of blood)
  7. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  8. Anxiety
  9. Conjunctivitis (pink eye)
  10. Conjunctivitis infective (infection of the conjunctiva)

What are the common drug interactions of Motrin and Valcyte, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Activated partial thromboplastin time prolonged
  2. Blood fibrinogen decreased
  3. Blood pressure inadequately controlled
  4. Cardiac arrest
  5. Coagulopathy (blood's ability to clot is impaired)
  6. Colitis (inflammation of colon)
  7. Cytomegalovirus test positive
  8. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  9. Hepatic failure (liver failure)
  10. Infective glossitis (tongue can become inflamed or infected)

10-19:

n/a

20-29:

  1. Chronic kidney disease
  2. Emotional distress
  3. Renal failure (kidney dysfunction)
  4. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  5. Anxiety
  6. Death
  7. Decreased activity
  8. Fear
  9. Haematoma (collection of blood outside the blood vessels)
  10. Impaired work ability

30-39:

  1. Abdominal pain upper
  2. Constipation
  3. Diarrhoea
  4. Fatigue (feeling of tiredness)
  5. Flatulence (flatus expelled through the anus)
  6. Functional gastrointestinal disorder (functional problem in separate organs of gastrointestinal system)
  7. Gastroenteritis (inflammation of stomach and intestine)
  8. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  9. Leukopenia (less number of white blood cells in blood)
  10. Nausea (feeling of having an urge to vomit)

40-49:

  1. Histoplasmosis (infection caused by breathing in spores of a fungus)
  2. Hiv infection
  3. Anaemia (lack of blood)

50-59:

  1. Blood creatinine increased
  2. Fatigue (feeling of tiredness)
  3. Glomerular filtration rate decreased
  4. Memory impairment
  5. Renal failure (kidney dysfunction)
  6. Renal injury (kidney injury)
  7. Skeletal injury (bone and supporting muscle injury)
  8. Tooth injury
  9. Viral load increased

60+:

n/a

What are the existing conditions these people have? *

  1. Hiv Infection: 7 people, 53.85%
  2. Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 4 people, 30.77%
  3. Cellulitis (infection under the skin): 4 people, 30.77%
  4. Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 2 people, 15.38%
  5. Dermatitis Infected (inflammation of the skin due to infection): 2 people, 15.38%
  6. Back Pain: 2 people, 15.38%
  7. Acquired Immunodeficiency Syndrome (disease of the human immune system caused by the human immunodeficiency virus (hiv)): 2 people, 15.38%
  8. Cytomegalovirus Infection: 1 person, 7.69%
  9. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Motrin and Valcyte:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Motrin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Valcyte:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Motrin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Valcyte and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen and valganciclovir hydrochloride (the active ingredients of Motrin and Valcyte, respectively), and Motrin and Valcyte (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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