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Movantik and Avinza drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Movantik (naloxegol oxalate) and Avinza (morphine sulfate). Common drug interactions include nephrogenic anaemia among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Movantik and Avinza. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Movantik?

Movantik has active ingredients of naloxegol oxalate. It is often used in constipation. eHealthMe is studying from 3,523 Movantik users. Check the latest studies of Movantik.

What is Avinza?

Avinza has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 1,728 Avinza users. Check the latest studies of Avinza.

On Jul, 14, 2026

15 people who take Movantik and Avinza together, and have interactions are studied.

Movantik and Avinza drug interactions.

What are the common drug interactions of Movantik and Avinza, by gender? *:

female:

  1. Nephrogenic anaemia (anaemia due to kidney disease)
  2. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  3. Renal disorder (kidney disease)
  4. Renal failure (kidney dysfunction)
  5. Chronic kidney disease
  6. Joint dislocation (a joint position is changed from normal position)
  7. Blood pressure increased

male:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Nephropathy (damage to or disease of a kidney)
  4. Renal injury (kidney injury)
  5. Nephrogenic anaemia (anaemia due to kidney disease)
  6. Hyperchlorhydria (gastric acid levels are higher in stomach)
  7. Rebound effect (take-back effect)

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 80.00%
  2. High Blood Cholesterol: 12 people, 80.00%
  3. Diabetes: 11 people, 73.33%
  4. Nausea (feeling of having an urge to vomit): 11 people, 73.33%
  5. Muscle Spasms (muscle contraction): 9 people, 60.00%
  6. Cough: 9 people, 60.00%
  7. Headache (pain in head): 9 people, 60.00%
  8. High Blood Pressure: 9 people, 60.00%
  9. Chest Pain: 9 people, 60.00%
  10. Indigestion: 9 people, 60.00%

* Approximation only. Some reports may have incomplete information.

Do you take Movantik and Avinza?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Movantik and Avinza:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Movantik:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Avinza:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Movantik and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Avinza and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on naloxegol oxalate and morphine sulfate (the active ingredients of Movantik and Avinza, respectively), and Movantik and Avinza (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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