Movantik and Compazine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Movantik (naloxegol oxalate) and Compazine (prochlorperazine maleate). Common drug interactions include muscle spasms among females and decreased appetite among males.

The phase IV clinical study analyzes what interactions people have when they take Movantik and Compazine. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Movantik?

Movantik has active ingredients of naloxegol oxalate. It is often used in constipation. eHealthMe is studying from 3,523 Movantik users. Check the latest studies of Movantik.

What is Compazine?

Compazine has active ingredients of prochlorperazine maleate. It is often used in indigestion. eHealthMe is studying from 13,646 Compazine users. Check the latest studies of Compazine.

On Jul, 12, 2026

40 people who take Movantik and Compazine together, and have interactions are studied.

Movantik and Compazine drug interactions.

What are the common drug interactions of Movantik and Compazine, by gender? *:

female:

Muscle spasms (muscle contraction)
Myalgia (muscle pain)
Oedema (fluid collection in tissue)
Oesophageal perforation (hole in oesophagus)
Osteoporosis (bones weak and more likely to break)
Ovarian cancer (cancer of ovary)
Platelet count decreased
Pulmonary embolism (blockage of the main artery of the lung)
Pyrexia (fever)
Staphylococcal infection (an infection with staphylococcus bacteria)

male:

Decreased appetite
Fatigue (feeling of tiredness)
Dehydration (dryness resulting from the removal of water)
Nephrolithiasis (calculi in the kidneys)
Pain
Dry skin
Faecaloma (hard mass of fecal matter)
Food intolerance (inability to have food)
Groin pain
Haemorrhage (bleeding)

What are the common drug interactions of Movantik and Compazine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Amylase increased
Lipase increased

40-49:

Hypophagia (reduced food intake)
Joint swelling
Oxygen saturation decreased
Platelet count decreased
Pneumonia
Abdominal pain
Dyspnoea exertional (breathlessness or shortness of breath)

50-59:

Fatigue (feeling of tiredness)
Asthenia (weakness)
Feeding disorder (when children refuse to eat certain food groups)
Hemiplegia (paralysis of one side of the body)
Malignant neoplasm progression (cancer tumour came back)
Osteonecrosis (death of bone)
Skin disorder (skin disease)
Abscess limb (limb infection)
Anal abscess
Cellulitis (infection under the skin)

60+:

Fall
Pneumonia
Death
Haemoglobin decreased
Head injury
Limb injury
Traumatic haemorrhage (a bleeding due to trauma)
Decreased appetite
Chest pain
Dehydration (dryness resulting from the removal of water)

What are the existing conditions these people have? *

Pain: 17 people, 42.50%
Nausea (feeling of having an urge to vomit): 17 people, 42.50%
Multiple Myeloma (cancer of the plasma cells): 9 people, 22.50%
Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 8 people, 20.00%
Systemic Mastocytosis (a condition caused by the accumulation of mast cells in more than one part of the body): 7 people, 17.50%
Stress And Anxiety: 6 people, 15.00%
Diarrhea: 3 people, 7.50%
Haematopoietic Neoplasm (clonal disorders of blood cells cause abnormal mass of tissue cell): 3 people, 7.50%
Drug Dependence: 2 people, 5.00%
Erection Problems: 2 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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