Movicol and Buscopan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Movicol (polyethylene glycol 3350) and Buscopan (hyoscine butylbromide). Common drug interactions include rash among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Movicol and Buscopan. It is created by eHealthMe based on reports of 90 people who take the same drugs from the FDA, and is updated regularly.

What is Movicol?

Movicol has active ingredients of polyethylene glycol 3350. It is often used in constipation. eHealthMe is studying from 14,249 Movicol users. Check the latest studies of Movicol.

What is Buscopan?

Buscopan has active ingredients of hyoscine butylbromide. eHealthMe is studying from 4,828 Buscopan users. Check the latest studies of Buscopan.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

90 people who take Movicol and Buscopan together, and have interactions are studied.

What are the common drug interactions of Movicol and Buscopan, by gender? *:

female:

Rash
Back pain
Intestinal perforation (complete penetration of the wall of the intestine)
Intussusception
Tremor (trembling or shaking movements in one or more parts of your body)
Urinary tract infection
White blood cell count decreased
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Blood cholesterol increased
Epstein-barr virus infection

male:

Diarrhoea
Small intestinal obstruction (blockage in small intestine)
Dermatitis allergic (inflammation of the skin due allergic reaction)
Neutropenia (an abnormally low number of neutrophils)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Platelet count decreased
Quadriplegia (a four limb paralysis)
Stomatitis (inflammation of mucous membrane of mouth)
Intestinal obstruction
Obstruction gastric (obstruction in stomach)

What are the common drug interactions of Movicol and Buscopan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Diarrhoea
Febrile neutropenia (fever with reduced white blood cells)
Haematochezia (passage of stools containing blood)
Hypophagia (reduced food intake)
Pleural effusion (water on the lungs)
Vomiting
Weight decreased
Haemoglobin decreased
Respiratory distress (difficulty in breathing)

10-19:

Abdominal pain

20-29:

Myocarditis (inflammation of heart muscle myocardium)
Chest pain
Colitis (inflammation of colon)

30-39:

Enteritis (inflammation of the small intestine)
Abdominal pain
Death
Spigelian hernia (a very rare abdominal wall hernia in the lower-mid abdomen)

40-49:

Pain
Abdominal pain
Adverse drug reaction
Arthralgia (joint pain)
Asthenia (weakness)
Avulsion fracture (bone fracture)
Back pain
Blood calcium increased
Chest pain
Completed suicide (act of taking one's own life)

50-59:

Metastatic neoplasm (spreadable cancer tumour)
Nausea (feeling of having an urge to vomit)
Neoplasm recurrence (reoccurrence of tumour)
Pelvic adhesions
Small intestinal obstruction (blockage in small intestine)
Weight decreased
Pyelonephritis (inflammation of kidney caused by bacteria)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Arteriospasm coronary (spasm of the large- or medium-sized coronary arteries)
Cardiovascular disorder (heart diseases)

60+:

Pyrexia (fever)
Anaemia (lack of blood)
Stomatitis (inflammation of mucous membrane of mouth)
Intestinal obstruction
Obstruction gastric (obstruction in stomach)
Tremor (trembling or shaking movements in one or more parts of your body)
Pain
Asthenia (weakness)
Dysaesthesia (abnormal sensation)
Muscle spasms (muscle contraction)

What are the existing conditions these people have? *

Pain: 14 people, 15.56%
Abdominal Pain: 14 people, 15.56%
Diabetes: 9 people, 10.00%
Hypokalemia (low potassium): 8 people, 8.89%
High Blood Cholesterol: 8 people, 8.89%
Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 8 people, 8.89%
Nausea (feeling of having an urge to vomit): 7 people, 7.78%
Rickets (softening of bones): 6 people, 6.67%
Restless Leg Syndrome (a powerful urge to move your legs): 6 people, 6.67%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 6 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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