Movicol and Trimethoprim drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Movicol (polyethylene glycol 3350) and Trimethoprim (trimethoprim). Common drug interactions include herpes zoster among females and abdominal distension among males.

The phase IV clinical study analyzes what interactions people have when they take Movicol and Trimethoprim. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Movicol?

Movicol has active ingredients of polyethylene glycol 3350. It is often used in constipation. eHealthMe is studying from 14,249 Movicol users. Check the latest studies of Movicol.

What is Trimethoprim?

Trimethoprim has active ingredients of trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 8,213 Trimethoprim users. Check the latest studies of Trimethoprim.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 03, 2026

40 people who take Movicol and Trimethoprim together, and have interactions are studied.

Movicol and Trimethoprim drug interactions.

What are the common drug interactions of Movicol and Trimethoprim, by gender? *:

female:

  1. Herpes zoster
  2. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  3. Skull fracture
  4. Breast cancer metastatic
  5. Asthenia (weakness)
  6. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  7. Influenza
  8. Pyrexia (fever)
  9. Arthralgia (joint pain)
  10. Cough

male:

  1. Abdominal distension
  2. Device dislocation
  3. Catheter site haemorrhage (bleeding at catheter site)
  4. Cough
  5. Depressed mood
  6. Emotional distress
  7. Fall
  8. Fungal infection
  9. Gait disturbance
  10. Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)

What are the common drug interactions of Movicol and Trimethoprim, by age (0-1 to 60+)? *:

0-1:

  1. Heart rate increased
  2. Hypothalamo-pituitary disorder (loss of function in an endocrine gland due to failure of the pituitary gland to secrete hormones which stimulate that gland's function)
  3. Peripheral coldness
  4. Respiratory rate increased (excess breathing rate/min)
  5. Skin discolouration (change of skin colour)
  6. Vomiting

2-9:

  1. Device dislocation
  2. Umbilical hernia (an outward bulging (protrusion) of the abdominal lining or part of the abdominal organ(s) through the area around the belly button)
  3. Weight gain poor
  4. Brain neoplasm malignant (brain cancer tumour)
  5. Dysphagia (a condition in which swallowing is difficult or painful)
  6. Pyrexia (fever)

10-19:

  1. Productive cough
  2. Respiratory tract congestion (blockage on respiratory system)
  3. Skin wound
  4. Abdominal distension
  5. Abdominal pain
  6. Anxiety
  7. Arthralgia (joint pain)
  8. Bradycardia (abnormally slow heart action)
  9. Catheter site haemorrhage (bleeding at catheter site)
  10. Cough

20-29:

n/a

30-39:

n/a

40-49:

  1. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  2. Infusion related reaction
  3. Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
  4. Pneumonia

50-59:

  1. Asthenia (weakness)
  2. Eye pain
  3. Fatigue (feeling of tiredness)
  4. Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
  5. Hypotension (abnormally low blood pressure)
  6. Oropharyngeal pain
  7. Pruritus (severe itching of the skin)
  8. Pyrexia (fever)
  9. Rash erythematous (redness of the skin)
  10. Skin exfoliation (removal of the oldest dead skin cells)

60+:

  1. Herpes zoster
  2. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  3. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  4. Influenza
  5. Fungal infection
  6. Myopathy (a muscular disease in which the muscle fibres do not function)
  7. Myositis (inflammation of the muscles)
  8. Speech disorder
  9. Arthralgia (joint pain)
  10. Asthenia (weakness)

What are the existing conditions these people have? *

  1. Pain: 9 people, 22.50%
  2. Diarrhea: 5 people, 12.50%
  3. Breast Cancer Metastatic: 5 people, 12.50%
  4. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 4 people, 10.00%
  5. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 4 people, 10.00%
  6. Respiratory Disorder (respiratory disease): 4 people, 10.00%
  7. Nervous System Disorder (a general class of medical conditions affecting the nervous system): 4 people, 10.00%
  8. Fungal Nail Infection: 3 people, 7.50%
  9. Fever: 3 people, 7.50%
  10. Infection: 3 people, 7.50%

* Approximation only. Some reports may have incomplete information.

Do you take Movicol and Trimethoprim?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Movicol and Trimethoprim:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Movicol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Trimethoprim:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Movicol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Trimethoprim and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on polyethylene glycol 3350 and trimethoprim (the active ingredients of Movicol and Trimethoprim, respectively), and Movicol and Trimethoprim (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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