Ms contin and Enulose drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ms contin (morphine sulfate) and Enulose (lactulose). Common drug interactions include melaena among females and neuropathy peripheral among males.

The phase IV clinical study analyzes what interactions people have when they take Ms contin and Enulose. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Ms contin?

Ms contin has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 69,289 Ms contin users. Check the latest studies of Ms contin.

What is Enulose?

Enulose has active ingredients of lactulose. It is often used in constipation. eHealthMe is studying from 711 Enulose users. Check the latest studies of Enulose.



On Jul, 06, 2026

33 people who take Ms contin and Enulose together, and have interactions are studied.

Ms contin and Enulose drug interactions.

What are the common drug interactions of Ms Contin and Enulose, by gender? *:

female:

  1. Melaena (the passage of black, tarry stools)
  2. Small intestinal obstruction (blockage in small intestine)
  3. Dyspnoea (difficult or laboured respiration)
  4. Nausea (feeling of having an urge to vomit)
  5. Oedema peripheral (superficial swelling)
  6. Erythema (redness of the skin)
  7. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  8. Non-cardiac chest pain
  9. Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
  10. Malaise (a feeling of general discomfort or uneasiness)

male:

  1. Neuropathy peripheral (surface nerve damage)
  2. Asthenia (weakness)
  3. Blood glucose decreased
  4. Blood pressure fluctuation
  5. Blood urea increased
  6. Bone disorder
  7. Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
  8. Cataract (clouding of the lens inside the eye)
  9. Confusional state
  10. Deafness

What are the common drug interactions of Ms Contin and Enulose, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Abdominal pain
  2. Bacteraemia (presence of bacteria in the blood)
  3. Device related infection
  4. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  5. Hypoglycaemia (deficiency of glucose in the bloodstream)
  6. Ileus (a painful obstruction of the ileum or other part of the intestine)
  7. Melaena (the passage of black, tarry stools)
  8. Small intestinal obstruction (blockage in small intestine)
  9. Dyspnoea (difficult or laboured respiration)
  10. Erythema (redness of the skin)

50-59:

  1. Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
  2. Abdominal abscess (collection of pus in abdomen)
  3. Cerebral infarction (less blood supply to brain resulting tissue damage)
  4. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  5. Deposit eye (yellow or white deposits in eyes)
  6. Organ failure
  7. Sepsis (a severe blood infection that can lead to organ failure and death)

60+:

  1. Nausea (feeling of having an urge to vomit)
  2. Agitation (state of anxiety or nervous excitement)
  3. Blood pressure fluctuation
  4. Blood urea increased
  5. Bone disorder
  6. Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
  7. Cataract (clouding of the lens inside the eye)
  8. Confusional state
  9. Deafness
  10. Decreased interest

What are the existing conditions these people have? *

  1. Prostate Cancer: 12 people, 36.36%
  2. Metastases To Bone (cancer spreads to bone): 12 people, 36.36%
  3. Nausea And Vomiting: 11 people, 33.33%
  4. Nausea (feeling of having an urge to vomit): 11 people, 33.33%
  5. Multiple Myeloma (cancer of the plasma cells): 9 people, 27.27%
  6. Stress And Anxiety: 4 people, 12.12%
  7. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 12.12%
  8. High Blood Cholesterol: 3 people, 9.09%
  9. Central Nervous System Stimulation: 3 people, 9.09%
  10. Depression: 3 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Ms contin and Enulose?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ms contin and Enulose:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ms contin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Enulose:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ms contin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Enulose and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on morphine sulfate and lactulose (the active ingredients of Ms contin and Enulose, respectively), and Ms contin and Enulose (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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