Ms contin and Epivir drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Ms contin (morphine sulfate) and Epivir (lamivudine). Common drug interactions include ascites among females and pneumonia among males.
The phase IV clinical study analyzes what interactions people have when they take Ms contin and Epivir. It is created by eHealthMe based on reports of 52 people who take the same drugs from the FDA, and is updated regularly.
What is Ms contin?
Ms contin has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 69,289 Ms contin users. Check the latest studies of Ms contin.
What is Epivir?
Epivir has active ingredients of lamivudine. It is often used in hiv infection. eHealthMe is studying from 16,870 Epivir users. Check the latest studies of Epivir.
52 people who take Ms contin and Epivir together, and have interactions are studied.

What are the common drug interactions of Ms Contin and Epivir, by gender? *:
female:
- Ascites (accumulation of fluid in the abdominal cavity)
- Complications of maternal exposure to therapeutic drugs
- Drug withdrawal syndrome neonatal (prenatal nas is caused by discontinuation of drugs taken by the pregnant mother)
- Foetal growth retardation (a baby in the womb fails to grow at the expected rate during the pregnancy)
- Hyperkalaemia (damage to or disease of the kidney)
- Neonatal disorder (disease of neonates)
- Oedema peripheral (superficial swelling)
- Pulmonary hypertension (increase in blood pressure in the lung artery)
- Tremor neonatal (excited neuromuscular activity of newborns)
- Weight increased
male:
- Pneumonia
- Brain stem haemorrhage (bleeding into structures of brain stem)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Asthenia (weakness)
- Chronic kidney disease
- Emotional distress
- Neuralgia (pain in one or more nerves)
- Osteopenia (a condition where bone mineral density is lower than normal)
- Bone density decreased
What are the common drug interactions of Ms Contin and Epivir, by age (0-1 to 60+)? *:
0-1:
- Alanine aminotransferase increased
- Anaemia neonatal
- Blood bilirubin increased
- Blood creatinine increased
- Blood lactic acid increased
- Blood triglycerides increased
- Complications of maternal exposure to therapeutic drugs
- Drug withdrawal syndrome neonatal (prenatal nas is caused by discontinuation of drugs taken by the pregnant mother)
- Hypertriglyceridaemia (excess of triglycerides in the blood)
- Hypocalcaemia (levels of calcium in blood serum are abnormally low)
2-9:
- Alanine aminotransferase increased
- Anaemia neonatal
- Blood bilirubin increased
- Blood creatinine increased
- Blood lactic acid increased
- Blood pyruvic acid increased
- Complications of maternal exposure to therapeutic drugs
- Drug withdrawal syndrome neonatal (prenatal nas is caused by discontinuation of drugs taken by the pregnant mother)
- Foetal growth retardation (a baby in the womb fails to grow at the expected rate during the pregnancy)
- Hyperbilirubinaemia neonatal (excess of bilirubin in the blood in newborn)
10-19:
n/a
20-29:
- Pancreatitis (inflammation of pancreas)
30-39:
- Hand fracture
- Rib fracture
- Bone density decreased
- Foot fracture
- Multiple fractures
- Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
- Osteopenia (a condition where bone mineral density is lower than normal)
- Renal failure (kidney dysfunction)
- Renal impairment (severely reduced kidney function)
- Vomiting
40-49:
- Blood sodium decreased
- Blood urea increased
- Bone mass decreased
- Bradycardia (abnormally slow heart action)
- Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
- Central line infection (infection by central line in icu)
- Cholangitis (infection of the bile duct)
- Coma (state of unconsciousness lasting more than six hours)
- Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
- Depression
50-59:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Gout (uric acid crystals building up in the body)
- Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium)
- Immune system disorder
- Insomnia (sleeplessness)
- Nephropathy (damage to or disease of a kidney)
- Nonketotic hyperglycaemic-hyperosmolar coma (a complication of diabetes mellitus (predominantly type 2) in which high blood sugars cause severe dehydration and coma)
- Osteopenia (a condition where bone mineral density is lower than normal)
- Renal failure (kidney dysfunction)
60+:
n/a
What are the existing conditions these people have? *
- Hiv Infection: 26 people, 50.00%
- Neuralgia (pain in one or more nerves): 10 people, 19.23%
- Pulmonary Hypertension Secondary (increase in blood pressure in the lung artery): 3 people, 5.77%
- Hepatitis B: 3 people, 5.77%
* Approximation only. Some reports may have incomplete information.
Do you take Ms contin and Epivir?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Ms contin and Epivir:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Ms contin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Epivir:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ms contin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Epivir and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Rasmy A, Rahal M, Kisana M, Ahmad S, Salah A, "Morphine induced thrombocytopenia: A case report", Journal of Case Reports and Images in Oncology, 2015 Dec .
- Rasmy A, Rahal M, Kisana M, Ahmad S, Salah A, "Morphine induced thrombocytopenia: A case report", Journal of Case Reports and Images in Oncology, 2015 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on morphine sulfate and lamivudine (the active ingredients of Ms contin and Epivir, respectively), and Ms contin and Epivir (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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