Ms contin and Hydrodiuril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ms contin (morphine sulfate) and Hydrodiuril (hydrochlorothiazide). Common drug interactions include fibromyalgia among females and myositis among males.

The phase IV clinical study analyzes what interactions people have when they take Ms contin and Hydrodiuril. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Ms contin?

Ms contin has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 69,289 Ms contin users. Check the latest studies of Ms contin.

What is Hydrodiuril?

Hydrodiuril has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 4,211 Hydrodiuril users. Check the latest studies of Hydrodiuril.



On Jul, 17, 2026

33 people who take Ms contin and Hydrodiuril together, and have interactions are studied.

Ms contin and Hydrodiuril drug interactions.

What are the common drug interactions of Ms Contin and Hydrodiuril, by gender? *:

female:

  1. Fibromyalgia (a long-term condition which causes pain all over the body)
  2. Haemoglobin increased
  3. Headache (pain in head)
  4. Hypoaesthesia (reduced sense of touch or sensation)
  5. Hypotension (abnormally low blood pressure)
  6. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
  7. Joint effusion (presence of extra fluid in joint covering)
  8. Loss of control of legs
  9. Metastases to lung (cancer spreads to lung)
  10. Osteoporosis (bones weak and more likely to break)

male:

  1. Myositis (inflammation of the muscles)
  2. Anxiety
  3. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  4. Chills (felling of cold)
  5. Corneal infection (corneal infection)
  6. Death
  7. Decreased appetite
  8. Depression
  9. Diarrhoea
  10. Disability

What are the common drug interactions of Ms Contin and Hydrodiuril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Anxiety
  2. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  3. Dyspnoea (difficult or laboured respiration)
  4. Pneumonia
  5. Swelling

50-59:

  1. Arthralgia (joint pain)
  2. Blood sodium decreased
  3. Joint swelling
  4. Pneumonia
  5. Pyoderma gangrenosum (ulcerating condition of skin that results in heaped borders with a typical appearance)
  6. Rash
  7. Therapeutic response decreased (less preventive response)
  8. Thirst
  9. Weight decreased
  10. Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)

60+:

  1. Myositis (inflammation of the muscles)
  2. Hypokalaemia (low potassium)
  3. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  4. Chills (felling of cold)
  5. Chronic kidney disease
  6. Death
  7. Decreased activity
  8. Decreased appetite
  9. Depression
  10. Diarrhoea

What are the existing conditions these people have? *

  1. Wheezing (a high-pitched whistling sound made while you breath): 8 people, 24.24%
  2. Dyspnea (difficult or laboured breathing): 8 people, 24.24%
  3. Polyarthritis (arthritis which involves 5 or more joints simultaneously): 7 people, 21.21%
  4. Nausea (feeling of having an urge to vomit): 7 people, 21.21%
  5. Menopausal Symptoms: 7 people, 21.21%
  6. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 21.21%
  7. High Blood Cholesterol: 6 people, 18.18%
  8. Insomnia (sleeplessness): 5 people, 15.15%
  9. Constipation: 5 people, 15.15%
  10. Juvenile Arthritis (arthritis-related condition that develops in children or teenagers): 5 people, 15.15%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ms contin and Hydrodiuril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ms contin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Hydrodiuril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ms contin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydrodiuril and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on morphine sulfate and hydrochlorothiazide (the active ingredients of Ms contin and Hydrodiuril, respectively), and Ms contin and Hydrodiuril (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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