Ms contin and Hyzaar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ms contin (morphine sulfate) and Hyzaar (hydrochlorothiazide; losartan potassium). Common drug interactions include myelodysplastic syndrome among females and cerebral ischaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Ms contin and Hyzaar. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Ms contin?

Ms contin has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 69,289 Ms contin users. Check the latest studies of Ms contin.

What is Hyzaar?

Hyzaar has active ingredients of hydrochlorothiazide; losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 16,614 Hyzaar users. Check the latest studies of Hyzaar.



On Jul, 18, 2026

28 people who take Ms contin and Hyzaar together, and have interactions are studied.

Ms contin and Hyzaar drug interactions.

What are the common drug interactions of Ms Contin and Hyzaar, by gender? *:

female:

  1. Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
  2. Neutrophil count abnormal (abnormal number of neutrophil a type of blood cell)
  3. Oral intake reduced
  4. Rigors (an episode of shaking or exaggerated shivering)
  5. Spinal column stenosis (narrowing of spinal column)
  6. Vomiting
  7. Weakness
  8. White blood cell count abnormal
  9. Headache (pain in head)
  10. Chills (felling of cold)

male:

  1. Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
  2. Completed suicide (act of taking one's own life)
  3. Malignant melanoma (skin cancer rises from melancytes)
  4. Neuropathy peripheral (surface nerve damage)
  5. Type 2 diabetes mellitus
  6. Urinary tract disorder
  7. Asthenia (weakness)
  8. Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
  9. Blood creatinine increased
  10. Chest pain

What are the common drug interactions of Ms Contin and Hyzaar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Diabetes mellitus inadequate control
  2. Diabetic coma
  3. Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
  4. Glycosuria (excretion of glucose into the urine)
  5. Hyperosmolar state (life-threatening emergency manifested by marked elevation of blood glucose)
  6. Malignant melanoma (skin cancer rises from melancytes)
  7. Neuropathy peripheral (surface nerve damage)
  8. Type 2 diabetes mellitus
  9. Urinary tract disorder
  10. Breast cancer

60+:

  1. Pyrexia (fever)
  2. Headache (pain in head)
  3. Blood glucose increased
  4. Body temperature decreased
  5. Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
  6. Chills (felling of cold)
  7. Completed suicide (act of taking one's own life)
  8. Crepitations (noises are produced by the rubbing of parts one against the other)
  9. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  10. Dehydration (dryness resulting from the removal of water)

What are the existing conditions these people have? *

  1. Depression: 6 people, 21.43%
  2. Lung Cancer - Non-Small Cell (lung cancer): 3 people, 10.71%
  3. Carcinoid Syndrome (syndrome includes flushing and diarrhoea, and, less frequently, heart failure and bronchoconstriction): 3 people, 10.71%
  4. Immunodeficiency Common Variable: 2 people, 7.14%
  5. Diabetes: 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Ms contin and Hyzaar?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ms contin and Hyzaar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ms contin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Hyzaar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ms contin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hyzaar and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on morphine sulfate and hydrochlorothiazide; losartan potassium (the active ingredients of Ms contin and Hyzaar, respectively), and Ms contin and Hyzaar (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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