Ms contin and Theo-dur drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Ms contin (morphine sulfate) and Theo-dur (theophylline). Common drug interactions include ileus paralytic among females and interstitial lung disease among males.
The phase IV clinical study analyzes what interactions people have when they take Ms contin and Theo-dur. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.
What is Ms contin?
Ms contin has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 69,289 Ms contin users. Check the latest studies of Ms contin.
What is Theo-dur?
Theo-dur has active ingredients of theophylline. It is often used in asthma. eHealthMe is studying from 4,451 Theo-dur users. Check the latest studies of Theo-dur.
24 people who take Ms contin and Theo-dur together, and have interactions are studied.

What are the common drug interactions of Ms Contin and Theo-Dur, by gender? *:
female:
- Ileus paralytic (obstruction of the intestine due to paralysis of the intestinal muscles)
- Infusion site erythema (reddening of the skin at infusion site)
- Infusion site mass
- Infusion site warmth
- Liver disorder (liver diseases)
- Oesophagitis (inflammation of oesophagus)
- Psychomotor seizures (complex partial seizures)
- Upper respiratory tract infection
- Swelling
- Cough
male:
- Interstitial lung disease
- Pneumonia
- Pneumocystis jiroveci pneumonia (fungal infection of the lungs)
- Renal failure acute (rapid kidney dysfunction)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Stridor
- Candida pneumonia (infection of lung by candida)
- Dilatation ventricular
- Dyspnoea (difficult or laboured respiration)
- Hypoxic encephalopathy (a condition that occurs when the entire brain is deprived of an adequate oxygen supply, but the deprivation isn't total)
What are the common drug interactions of Ms Contin and Theo-Dur, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Swelling
- Type 2 diabetes mellitus
- Vomiting
- Disease progression
- Dyspnoea (difficult or laboured respiration)
- Platelet count decreased
- Anaemia (lack of blood)
- Bipolar disorder (mood disorder)
- Candidiasis (candidiasis or thrush is a fungal infection)
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
50-59:
- Cough
- Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
- Angioedema (rapid swelling of the dermis)
- Dyspnoea (difficult or laboured respiration)
- Erythema (redness of the skin)
- Hypotension (abnormally low blood pressure)
- Hypoxia (low oxygen in tissues)
- Pneumonia
- Pruritus (severe itching of the skin)
- Pruritus generalised (generalized itching)
60+:
- Interstitial lung disease
- Pneumonia
- Pneumocystis jiroveci pneumonia (fungal infection of the lungs)
- Renal failure acute (rapid kidney dysfunction)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Stridor
- Candida pneumonia (infection of lung by candida)
- Dilatation ventricular
- Hypoxic encephalopathy (a condition that occurs when the entire brain is deprived of an adequate oxygen supply, but the deprivation isn't total)
- Malignant neoplasm progression (cancer tumour came back)
What are the existing conditions these people have? *
- Non-Small Cell Lung Cancer Stage Iiib: 4 people, 16.67%
- Non-Small Cell Lung Cancer Recurrent (type of epithelial lung cancer reoccurrence): 4 people, 16.67%
- Lung Adenocarcinoma Stage Iii (the cancer has spread to nearby tissue or too far away lymph nodes): 4 people, 16.67%
- Cancer Pain: 4 people, 16.67%
- Hypersensitivity: 3 people, 12.50%
- Sleep Disorder: 2 people, 8.33%
- Ovarian Cancer (cancer of ovary): 2 people, 8.33%
- Nausea (feeling of having an urge to vomit): 2 people, 8.33%
- Muscle Spasms (muscle contraction): 2 people, 8.33%
- Itching: 2 people, 8.33%
* Approximation only. Some reports may have incomplete information.
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Ms contin and Theo-dur:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Ms contin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Theo-dur:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ms contin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Theo-dur and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Korang-Yeboah M, Rahman Z, Shah D, Mohammad A, Wu S, Siddiqui A, Khan MA, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International journal of pharmaceutics, 2016 Feb .
- Dhaval MK, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International Journal of Pharmaceutics, 2016 Jan .
- Rasmy A, Rahal M, Kisana M, Ahmad S, Salah A, "Morphine induced thrombocytopenia: A case report", Journal of Case Reports and Images in Oncology, 2015 Dec .
- Korang-Yeboah M, Rahman Z, Shah D, Mohammad A, Wu S, Siddiqui A, Khan MA, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International journal of pharmaceutics, 2016 Feb .
- Dhaval MK, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International Journal of Pharmaceutics, 2016 Jan .
- Rasmy A, Rahal M, Kisana M, Ahmad S, Salah A, "Morphine induced thrombocytopenia: A case report", Journal of Case Reports and Images in Oncology, 2015 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on morphine sulfate and theophylline (the active ingredients of Ms contin and Theo-dur, respectively), and Ms contin and Theo-dur (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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