Msm and Calcium citrate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Msm (methylsulfonylmethane) and Calcium citrate (calcium). Common drug interactions include constipation among females and dry eye among males.

The phase IV clinical study analyzes what interactions people have when they take Msm and Calcium citrate. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.

What is Msm?

Msm has active ingredients of methylsulfonylmethane. It is often used in joint pain. eHealthMe is studying from 1,210 Msm users. Check the latest studies of Msm.

What is Calcium citrate?

Calcium citrate has active ingredients of calcium. It is often used in osteopenia. eHealthMe is studying from 12,606 Calcium citrate users. Check the latest studies of Calcium citrate.

On Jul, 07, 2026

45 people who take Msm and Calcium citrate together, and have interactions are studied.

Msm and Calcium citrate drug interactions.

What are the common drug interactions of Msm and Calcium Citrate, by gender? *:

female:

Constipation
Lung disorder (lung disease)
Headache (pain in head)
Pneumonia
Sepsis (a severe blood infection that can lead to organ failure and death)
Urinary tract infection
Drug effect decreased
Pneumonia klebsiella (pneumonia caused by bacteria klebsiella)
White blood cell count increased
Arteriospasm coronary (spasm of the large- or medium-sized coronary arteries)

male:

Dry eye (lack of adequate tears)
Eosinophil count increased
Drug ineffective
Hypersensitivity
Hypoaesthesia (reduced sense of touch or sensation)
Hypotension (abnormally low blood pressure)
Insomnia (sleeplessness)
Neuropathy peripheral (surface nerve damage)
Oedema peripheral (superficial swelling)
Presyncope

What are the common drug interactions of Msm and Calcium Citrate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Alopecia (absence of hair from areas of the body)

50-59:

Arteriospasm coronary (spasm of the large- or medium-sized coronary arteries)
Depression
Hypoglycaemia (deficiency of glucose in the bloodstream)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Panic attack
Drug ineffective
Fibromyalgia (a long-term condition which causes pain all over the body)
Syncope (loss of consciousness with an inability to maintain postural tone)

60+:

Constipation
Drug effect decreased
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Weight decreased
Clostridium test positive
Diarrhoea
Impaired work ability
Abasia (inability to walk)
Abdominal pain
Abdominal pain upper

What are the existing conditions these people have? *

Pain: 12 people, 26.67%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 9 people, 20.00%
Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously): 5 people, 11.11%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 8.89%
Gastric Disorder (disease of stomach): 4 people, 8.89%
High Blood Cholesterol: 3 people, 6.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 6.67%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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