Mucinex and Alkeran drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mucinex (guaifenesin) and Alkeran (melphalan). Common drug interactions include cardiomegaly among females and abscess jaw among males.

The phase IV clinical study analyzes what interactions people have when they take Mucinex and Alkeran. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Mucinex?

Mucinex has active ingredients of guaifenesin. It is often used in cough. eHealthMe is studying from 29,749 Mucinex users. Check the latest studies of Mucinex.

What is Alkeran?

Alkeran has active ingredients of melphalan. eHealthMe is studying from 5,429 Alkeran users. Check the latest studies of Alkeran.

On Aug, 02, 2026

15 people who take Mucinex and Alkeran together, and have interactions are studied.

What are the common drug interactions of Mucinex and Alkeran, by gender? *:

female:

Cardiomegaly (increased size of heart than normal)
Chills (felling of cold)
Colitis (inflammation of colon)
Constipation
Diarrhoea
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Emotional distress
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
Empyema (collection of pus in a cavity in the body)
Exostosis (formation of new bone on the surface of a bone)

male:

Abscess jaw (tooth abscess or root abscess)
Anaemia of chronic disease
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
Brain injury
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Cardiac failure congestive
Cardiomegaly (increased size of heart than normal)
Cataract (clouding of the lens inside the eye)

What are the common drug interactions of Mucinex and Alkeran, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anaemia of chronic disease
Anxiety
Arteriosclerosis (thickening and hardening of arteries)
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Arthropathy
Asthenia (weakness)
Atelectasis (partial or complete collapse of the lung)
Back pain
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)

30-39:

n/a

40-49:

n/a

50-59:

Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Febrile neutropenia (fever with reduced white blood cells)
Fluid retention (an abnormal accumulation of fluid in the blood)
Gallbladder disorder
Hip fracture
Hypertension (high blood pressure)
Osteoporosis (bones weak and more likely to break)
Weight decreased
Wound infection staphylococcal

60+:

Anxiety
Back pain
Emotional distress
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
Empyema (collection of pus in a cavity in the body)
Exostosis (formation of new bone on the surface of a bone)
Fatigue (feeling of tiredness)
Granuloma (a small area of inflammation due to tissue injury)
Haematochezia (passage of stools containing blood)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 1 person, 6.67%
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 1 person, 6.67%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 6.67%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 1 person, 6.67%
Bronchitis Chronic (inflammation of the mucous membrane in the bronchial tubes- chronic): 1 person, 6.67%
Acne (skin problems that cause pimples): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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