Mucinex and Combivir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mucinex (guaifenesin) and Combivir (lamivudine; zidovudine). Common drug interactions include anhedonia among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Mucinex and Combivir. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Mucinex?

Mucinex has active ingredients of guaifenesin. It is often used in cough. eHealthMe is studying from 29,749 Mucinex users. Check the latest studies of Mucinex.

What is Combivir?

Combivir has active ingredients of lamivudine; zidovudine. It is often used in hiv infection. eHealthMe is studying from 15,450 Combivir users. Check the latest studies of Combivir.



On Jul, 11, 2026

22 people who take Mucinex and Combivir together, and have interactions are studied.

Mucinex and Combivir drug interactions.

What are the common drug interactions of Mucinex and Combivir, by gender? *:

female:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Emotional distress
  3. Neck pain
  4. Osteopenia (a condition where bone mineral density is lower than normal)
  5. Pain
  6. Ankle fracture
  7. Anxiety
  8. Arthralgia (joint pain)
  9. Back pain
  10. Bacterial infection

male:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Renal impairment (severely reduced kidney function)
  4. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  5. Depression
  6. Hand fracture
  7. Hip arthroplasty
  8. Multiple fractures
  9. Multiple injuries
  10. Rotator cuff repair

What are the common drug interactions of Mucinex and Combivir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Neutropenia (an abnormally low number of neutrophils)
  2. Pneumonia

30-39:

n/a

40-49:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Chronic kidney disease
  4. Emotional distress
  5. Osteoporosis (bones weak and more likely to break)
  6. Pain
  7. Renal failure (kidney dysfunction)
  8. Bone density decreased
  9. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  10. Hip arthroplasty

50-59:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Emotional distress
  4. Pain
  5. Osteopenia (a condition where bone mineral density is lower than normal)
  6. Osteoporosis (bones weak and more likely to break)
  7. Chronic kidney disease
  8. Fracture
  9. Multiple injuries
  10. Renal failure (kidney dysfunction)

60+:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Bone density decreased
  3. Pain in extremity
  4. Anxiety
  5. Blood creatinine increased
  6. Chronic kidney disease
  7. Joint injury
  8. Renal impairment (severely reduced kidney function)
  9. Emotional distress
  10. Osteopenia (a condition where bone mineral density is lower than normal)

What are the existing conditions these people have? *

  1. Hiv Infection: 20 people, 90.91%
  2. Pain: 4 people, 18.18%
  3. Constipation: 4 people, 18.18%
  4. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 13.64%
  5. Depression: 3 people, 13.64%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 13.64%
  7. Hypersensitivity: 3 people, 13.64%
  8. High Blood Pressure: 2 people, 9.09%
  9. Asthma: 2 people, 9.09%
  10. Calcium Deficiency (lack of calcium): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Mucinex and Combivir?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Mucinex and Combivir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Mucinex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Combivir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mucinex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Combivir and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on guaifenesin and lamivudine; zidovudine (the active ingredients of Mucinex and Combivir, respectively), and Mucinex and Combivir (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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