Mucinex and Elavil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mucinex (guaifenesin) and Elavil (amitriptyline hydrochloride). Common drug interactions include pneumonia among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Mucinex and Elavil. It is created by eHealthMe based on reports of 77 people who take the same drugs from the FDA, and is updated regularly.

What is Mucinex?

Mucinex has active ingredients of guaifenesin. It is often used in cough. eHealthMe is studying from 29,749 Mucinex users. Check the latest studies of Mucinex.

What is Elavil?

Elavil has active ingredients of amitriptyline hydrochloride. It is often used in depression. eHealthMe is studying from 20,724 Elavil users. Check the latest studies of Elavil.

On Apr, 27, 2026

77 people who take Mucinex and Elavil together, and have interactions are studied.

What are the common drug interactions of Mucinex and Elavil, by gender? *:

female:

Pneumonia
Fatigue (feeling of tiredness)
Renal failure (kidney dysfunction)
Asthenia (weakness)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Dysarthria (speech disorder)
Loss of consciousness
Speech disorder
Suicide attempt
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))

male:

Pneumonia
Anxiety
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Dyspnoea (difficult or laboured respiration)
Sputum discoloured
Urinary tract infection
Vision blurred
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cerebral atrophy (decrement in size of brain)
Encephalopathy (functioning of the brain is affected by some agent or condition)

What are the common drug interactions of Mucinex and Elavil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Asthma
Pancreatitis acute (sudden inflammation of pancreas)
Pharyngeal erythema (pharyngeal redness)
Rhinitis allergic (inflammation of the nasal airways due to allergy)
Pruritus (severe itching of the skin)
Urticaria (rash of round, red welts on the skin that itch intensely)

40-49:

Anxiety
Chronic kidney disease
Pneumonia
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Bone density decreased
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Emotional distress
Fracture
Hip arthroplasty
Osteopenia (a condition where bone mineral density is lower than normal)

50-59:

Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Loss of consciousness
Suicide attempt
Fatigue (feeling of tiredness)
Pneumonia
Dizziness
Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Pain in extremity
Pulmonary mass

60+:

Pneumonia
Asthenia (weakness)
Pain
Sepsis (a severe blood infection that can lead to organ failure and death)
Sputum discoloured
Urinary tract infection
Vision blurred
Anaemia (lack of blood)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cerebral atrophy (decrement in size of brain)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 21 people, 27.27%
Pain: 13 people, 16.88%
Nausea (feeling of having an urge to vomit): 7 people, 9.09%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 9.09%
Fibromyalgia (a long-term condition which causes pain all over the body): 7 people, 9.09%
Sleep Disorder: 5 people, 6.49%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 5 people, 6.49%
Asthma: 5 people, 6.49%
Stress And Anxiety: 4 people, 5.19%

* Approximation only. Some reports may have incomplete information.

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