Mucinex and Prograf drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mucinex (guaifenesin) and Prograf (tacrolimus). Common drug interactions include pain among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Mucinex and Prograf. It is created by eHealthMe based on reports of 58 people who take the same drugs from the FDA, and is updated regularly.

What is Mucinex?

Mucinex has active ingredients of guaifenesin. It is often used in cough. eHealthMe is studying from 29,749 Mucinex users. Check the latest studies of Mucinex.

What is Prograf?

Prograf has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 42,230 Prograf users. Check the latest studies of Prograf.

On Jul, 18, 2026

58 people who take Mucinex and Prograf together, and have interactions are studied.

What are the common drug interactions of Mucinex and Prograf, by gender? *:

female:

Pain
Pruritus (severe itching of the skin)
Renal failure (kidney dysfunction)
Somnolence (a state of near-sleep, a strong desire for sleep)
Transplant failure (transplantation failed to meet outcome)
Urine output decreased
Dyspnoea (difficult or laboured respiration)
Decreased appetite
Lower respiratory tract infection
Pyrexia (fever)

male:

Renal failure (kidney dysfunction)
Chronic kidney disease
Hip arthroplasty
Infection
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Pain
Rotator cuff repair
Spinal cord injury
Upper limb fracture

What are the common drug interactions of Mucinex and Prograf, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal discomfort
Cholangitis (infection of the bile duct)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Headache (pain in head)
Portal hypertension (increase in the blood pressure within a system of veins called the portal venous system)
Portal vein thrombosis (venous thrombosis affecting the hepatic portal vein)
Tremor (trembling or shaking movements in one or more parts of your body)
Varices oesophageal (enlarged and swollen veins at the bottom of the oesophagus, near the stomach)
Visual impairment

30-39:

Aphonia (inability to produce voice)
Throat irritation
Upper-airway cough syndrome
Wheezing (a high-pitched whistling sound made while you breath)
Brain injury
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Sepsis (a severe blood infection that can lead to organ failure and death)
Burning sensation
Carbon monoxide poisoning

40-49:

Somnolence (a state of near-sleep, a strong desire for sleep)
Transplant failure (transplantation failed to meet outcome)
Urine output decreased
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Emotional distress
Hip arthroplasty
Osteopenia (a condition where bone mineral density is lower than normal)

50-59:

Appetite disorder (abnormal eating habits)
Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Rhinovirus infection
Vomiting
Weight decreased

60+:

Dyspnoea (difficult or laboured respiration)
Chronic kidney disease
Sinusitis (inflammation of sinus)
Asthenia (weakness)
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Blood pressure increased
Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
Carbon dioxide decreased
Graft loss (graft failure)

What are the existing conditions these people have? *

Indigestion: 8 people, 13.79%
Cystic Fibrosis (disease of the secretary glands): 6 people, 10.34%
Pain: 5 people, 8.62%
Nausea (feeling of having an urge to vomit): 4 people, 6.90%
Immunodeficiency Common Variable: 4 people, 6.90%
High Blood Pressure: 4 people, 6.90%
High Blood Cholesterol: 4 people, 6.90%
Pneumonia: 3 people, 5.17%
Nausea And Vomiting: 3 people, 5.17%
Nasopharyngitis (inflammation of the nasopharynx): 3 people, 5.17%

* Approximation only. Some reports may have incomplete information.

Do you take Mucinex and Prograf?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously