Mucinex and Xyzal drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mucinex (guaifenesin) and Xyzal (levocetirizine dihydrochloride). Common drug interactions include headache among females and chest discomfort among males.

The phase IV clinical study analyzes what interactions people have when they take Mucinex and Xyzal. It is created by eHealthMe based on reports of 317 people who take the same drugs from the FDA, and is updated regularly.

What is Mucinex?

Mucinex has active ingredients of guaifenesin. It is often used in cough. eHealthMe is studying from 29,749 Mucinex users. Check the latest studies of Mucinex.

What is Xyzal?

Xyzal has active ingredients of levocetirizine dihydrochloride. It is often used in allergies. eHealthMe is studying from 21,479 Xyzal users. Check the latest studies of Xyzal.



On Apr, 15, 2026

317 people who take Mucinex and Xyzal together, and have interactions are studied.

Mucinex and Xyzal drug interactions.

What are the common drug interactions of Mucinex and Xyzal, by gender? *

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What are the common drug interactions of Mucinex and Xyzal, by age (0-1 to 60+)? *

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What are the existing conditions these people have? *

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* Approximation only. Some reports may have incomplete information.

Do you take Mucinex and Xyzal?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Mucinex and Xyzal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Mucinex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Xyzal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mucinex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Xyzal and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on guaifenesin and levocetirizine dihydrochloride (the active ingredients of Mucinex and Xyzal, respectively), and Mucinex and Xyzal (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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