Mucomyst and Solu-medrol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mucomyst (acetylcysteine) and Solu-medrol (methylprednisolone sodium succinate). Common drug interactions include renal failure among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Mucomyst and Solu-medrol. It is created by eHealthMe based on reports of 67 people who take the same drugs from the FDA, and is updated regularly.

What is Mucomyst?

Mucomyst has active ingredients of acetylcysteine. eHealthMe is studying from 1,835 Mucomyst users. Check the latest studies of Mucomyst.

What is Solu-medrol?

Solu-medrol has active ingredients of methylprednisolone sodium succinate. It is often used in multiple sclerosis. eHealthMe is studying from 39,410 Solu-medrol users. Check the latest studies of Solu-medrol.



On Aug, 03, 2026

67 people who take Mucomyst and Solu-medrol together, and have interactions are studied.

Mucomyst and Solu-medrol drug interactions.

What are the common drug interactions of Mucomyst and Solu-Medrol, by gender? *:

female:

  1. Renal failure (kidney dysfunction)
  2. Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
  3. Acinetobacter infection (infection by group of bacteria commonly found in soil and water)
  4. Diarrhoea haemorrhagic (bloody diarrhoea)
  5. Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
  6. Infection
  7. Pleural effusion (water on the lungs)
  8. Tooth abscess (pus formation in tooth)
  9. Arrhythmia (irregular heartbeat)
  10. Cardiac arrest

male:

  1. Pneumonia
  2. Pyrexia (fever)
  3. Constipation
  4. Respiratory failure (inadequate gas exchange by the respiratory system)
  5. Acute respiratory distress syndrome
  6. Pain
  7. Respiratory distress (difficulty in breathing)
  8. Blood creatinine increased
  9. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  10. Hypoxia (low oxygen in tissues)

What are the common drug interactions of Mucomyst and Solu-Medrol, by age (0-1 to 60+)? *:

0-1:

  1. Bronchiolitis (inflammation of the membranes lining the bronchioles in lungs)
  2. Muscle spasticity (tight or stiff muscles and an inability to control those muscles)
  3. Otitis media (inflammation of the middle ear)
  4. Otitis media acute (rapid inflammation of the middle ear)

2-9:

  1. Acinetobacter infection (infection by group of bacteria commonly found in soil and water)
  2. Diarrhoea
  3. Diarrhoea haemorrhagic (bloody diarrhoea)
  4. Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
  5. Haematoma (collection of blood outside the blood vessels)
  6. Pleural effusion (water on the lungs)
  7. Pyrexia (fever)
  8. Septic shock (shock due to blood infection)
  9. Tooth abscess (pus formation in tooth)

10-19:

n/a

20-29:

n/a

30-39:

  1. Acidosis (build-up of carbon dioxide in the blood)
  2. Acute respiratory distress syndrome
  3. Anaemia (lack of blood)
  4. Asthenia (weakness)
  5. Bandaemia (excess of band cells (immature white blood cells) released by the bone marrow into the blood)
  6. Blood creatinine increased
  7. Blood urea increased
  8. Bronchial haemorrhage (bleeding in bronchia)
  9. Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
  10. Constipation

40-49:

  1. Lung infection
  2. Anisocytosis (patient's red blood cells are of unequal size)
  3. Asthenia (weakness)
  4. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  5. Cardiac tamponade (fluid accumulates in heart covering)
  6. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  7. Connective tissue disorder (any disease that has the connective tissues of the body)
  8. Ejection fraction (the percentage of blood that is pumped out of a filled ventricle as a result of a heartbeat)
  9. Hilar lymphadenopathy (disease of the lymph nodes due to infection)
  10. Hyperglycaemia (high blood sugar)

50-59:

  1. Acute stress disorder
  2. Alveolitis allergic (inflammation of the alveoli within the lung caused by hypersensitivity to inhaled organic dusts)
  3. Anxiety
  4. Blood alkaline phosphatase increased
  5. Cardiac valve disease (heart valve disease)
  6. Dry mouth
  7. Ejection fraction decreased (systolic heart failure)
  8. Emotional distress
  9. Fear
  10. Gamma-glutamyltransferase increased

60+:

  1. Anxiety
  2. Pneumonia
  3. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  4. Tricuspid valve incompetence (inefficient heart valve)
  5. Lung neoplasm malignant (cancer tumour of lung)
  6. Anuria (failure of the kidneys to produce urine)
  7. Arthralgia (joint pain)
  8. Cardiac arrest
  9. Dehydration (dryness resulting from the removal of water)
  10. Emotional distress

What are the existing conditions these people have? *

  1. Pain: 13 people, 19.40%
  2. High Blood Pressure: 9 people, 13.43%
  3. Nausea (feeling of having an urge to vomit): 7 people, 10.45%
  4. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 7 people, 10.45%
  5. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 7 people, 10.45%
  6. Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 6 people, 8.96%
  7. Agitation (state of anxiety or nervous excitement): 5 people, 7.46%
  8. Nausea And Vomiting: 5 people, 7.46%
  9. Ventricular Tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 4 people, 5.97%
  10. Headache (pain in head): 4 people, 5.97%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Mucomyst and Solu-medrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Mucomyst:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Solu-medrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mucomyst and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Solu-medrol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on acetylcysteine and methylprednisolone sodium succinate (the active ingredients of Mucomyst and Solu-medrol, respectively), and Mucomyst and Solu-medrol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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