Multaq and Atacand drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Multaq (dronedarone hydrochloride) and Atacand (candesartan cilexetil). Common drug interactions include pulmonary hypertension among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Multaq and Atacand. It is created by eHealthMe based on reports of 66 people who take the same drugs from the FDA, and is updated regularly.

What is Multaq?

Multaq has active ingredients of dronedarone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 11,053 Multaq users. Check the latest studies of Multaq.

What is Atacand?

Atacand has active ingredients of candesartan cilexetil. It is often used in high blood pressure. eHealthMe is studying from 22,473 Atacand users. Check the latest studies of Atacand.



On Aug, 02, 2026

66 people who take Multaq and Atacand together, and have interactions are studied.

Multaq and Atacand drug interactions.

What are the common drug interactions of Multaq and Atacand, by gender? *:

female:

  1. Pulmonary hypertension (increase in blood pressure in the lung artery)
  2. Abdominal pain
  3. Blood pressure decreased
  4. Fatigue (feeling of tiredness)
  5. Pruritus (severe itching of the skin)
  6. Alanine aminotransferase increased
  7. Aspartate aminotransferase increased
  8. Bladder cancer
  9. Drug hypersensitivity
  10. Gamma-glutamyltransferase increased

male:

  1. Dyspnoea (difficult or laboured respiration)
  2. Renal failure (kidney dysfunction)
  3. Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
  4. Abnormal behaviour
  5. Alanine aminotransferase increased
  6. Atrophic vulvovaginitis (inflammation of the vulva)
  7. Blood pressure decreased
  8. Bradycardia (abnormally slow heart action)
  9. Cheilitis (infection of lips)
  10. Completed suicide (act of taking one's own life)

What are the common drug interactions of Multaq and Atacand, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Blood pressure decreased
  2. Diarrhoea
  3. Hypoglycaemia (deficiency of glucose in the bloodstream)
  4. International normalised ratio decreased
  5. Somnolence (a state of near-sleep, a strong desire for sleep)

50-59:

  1. Hyperthyroidism (over activity of the thyroid gland)
  2. Interstitial lung disease
  3. Nausea (feeling of having an urge to vomit)
  4. Pyrexia (fever)
  5. Restrictive pulmonary disease (reduction in total lung capacity)
  6. Hepatitis toxic
  7. Blood bilirubin increased
  8. Cerebral haemorrhage (bleeding within the brain)
  9. Chest pain
  10. Cough

60+:

  1. Renal failure (kidney dysfunction)
  2. Diarrhoea
  3. Azotaemia (excess of urea or other nitrogenous compounds in the blood)
  4. Decreased appetite
  5. Bradycardia (abnormally slow heart action)
  6. Gait disturbance
  7. Hepatocellular injury (liver injury)
  8. Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
  9. Alanine aminotransferase increased
  10. Cholestasis (a condition where bile cannot flow from the liver to the duodenum)

What are the existing conditions these people have? *

  1. Arrhythmias (irregular heartbeat): 5 people, 7.58%

* Approximation only. Some reports may have incomplete information.

Do you take Multaq and Atacand?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Multaq and Atacand:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Multaq:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Atacand:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Multaq and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Atacand and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on dronedarone hydrochloride and candesartan cilexetil (the active ingredients of Multaq and Atacand, respectively), and Multaq and Atacand (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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