Multaq and Codeine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Multaq (dronedarone hydrochloride) and Codeine (codeine sulfate). Common drug interactions include drug hypersensitivity among females and hepatic vein thrombosis among males.
The phase IV clinical study analyzes what interactions people have when they take Multaq and Codeine. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.
What is Multaq?
Multaq has active ingredients of dronedarone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 11,053 Multaq users. Check the latest studies of Multaq.
What is Codeine?
Codeine has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 42,342 Codeine users. Check the latest studies of Codeine.
15 people who take Multaq and Codeine together, and have interactions are studied.

What are the common drug interactions of Multaq and Codeine, by gender? *:
female:
- Drug hypersensitivity
- Fatigue (feeling of tiredness)
- Herpes zoster
- Stress
- Weight decreased
- Abdominal distension
- Chronic kidney disease
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Generalised oedema (swelling all over the body)
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
male:
- Hepatic vein thrombosis (obstruction in the veins of the liver caused by a blood clot)
- Hypoxia (low oxygen in tissues)
- Blood calcium increased
- Blood creatinine increased
- Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
- Death
- Drug hypersensitivity
- Fear
- Fistula (an abnormal connection or passageway between two)
- Haematoma (collection of blood outside the blood vessels)
What are the common drug interactions of Multaq and Codeine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Abdominal distension
- Generalised oedema (swelling all over the body)
50-59:
- Death
60+:
- Drug hypersensitivity
- Hepatic vein thrombosis (obstruction in the veins of the liver caused by a blood clot)
- Fatigue (feeling of tiredness)
- Herpes zoster
- Stress
- Weight decreased
- Abscess intestinal (collections of pus-intestinal)
- Blood calcium increased
- Blood creatinine increased
- Chronic kidney disease
What are the existing conditions these people have? *
- Osteoporosis (bones weak and more likely to break): 1 person, 6.67%
- Non-Small Cell Lung Cancer Metastatic (type of epithelial lung cancer spreads to other parts): 1 person, 6.67%
- High Blood Pressure: 1 person, 6.67%
- Headache (pain in head): 1 person, 6.67%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 6.67%
- Diarrhea: 1 person, 6.67%
- Acne (skin problems that cause pimples): 1 person, 6.67%
* Approximation only. Some reports may have incomplete information.
Do you take Multaq and Codeine?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Multaq and Codeine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Multaq:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Codeine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Multaq and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Codeine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on dronedarone hydrochloride and codeine sulfate (the active ingredients of Multaq and Codeine, respectively), and Multaq and Codeine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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