Multaq and Prinivil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Multaq (dronedarone hydrochloride) and Prinivil (lisinopril). Common drug interactions include acute pulmonary oedema among females and coagulopathy among males.

The phase IV clinical study analyzes what interactions people have when they take Multaq and Prinivil. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Multaq?

Multaq has active ingredients of dronedarone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 11,053 Multaq users. Check the latest studies of Multaq.

What is Prinivil?

Prinivil has active ingredients of lisinopril. It is often used in high blood pressure. eHealthMe is studying from 20,152 Prinivil users. Check the latest studies of Prinivil.



On Jul, 07, 2026

22 people who take Multaq and Prinivil together, and have interactions are studied.

Multaq and Prinivil drug interactions.

What are the common drug interactions of Multaq and Prinivil, by gender? *:

female:

  1. Acute pulmonary oedema (sudden deposit of fluid in the lung))
  2. Brain natriuretic peptide increased
  3. Cardiac failure congestive
  4. Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
  5. Death
  6. Dyspnoea (difficult or laboured respiration)
  7. Fatigue (feeling of tiredness)
  8. Hallucination (an experience involving the perception of something not present)
  9. Hypoxia (low oxygen in tissues)
  10. Leukocytosis (increased white blood cells)

male:

  1. Coagulopathy (blood's ability to clot is impaired)
  2. Haematuria (presence of blood in urine)
  3. Pain in extremity
  4. Peripheral arterial occlusive disease (reproducible ischemic muscle pain)
  5. Peripheral swelling
  6. Thrombosis (formation of a blood clot inside a blood vessel)
  7. Abdominal discomfort
  8. Asthenia (weakness)
  9. Atrial thrombosis (blood clot that develops in an artery)
  10. Brain natriuretic peptide increased

What are the common drug interactions of Multaq and Prinivil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Atrial thrombosis (blood clot that develops in an artery)
  2. Brain natriuretic peptide increased
  3. Cardiac failure congestive
  4. Dyspepsia (indigestion)
  5. Ejection fraction decreased (systolic heart failure)
  6. Hepatitis (inflammation of the liver)
  7. Hepatocellular injury (liver injury)
  8. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  9. Hypotension (abnormally low blood pressure)
  10. Ocular icterus (presence of jaundice seen in the sclera of the eye)

30-39:

n/a

40-49:

n/a

50-59:

  1. Death

60+:

  1. Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
  2. Coagulopathy (blood's ability to clot is impaired)
  3. Pain in extremity
  4. Peripheral arterial occlusive disease (reproducible ischemic muscle pain)
  5. Peripheral swelling
  6. Thrombosis (formation of a blood clot inside a blood vessel)
  7. Abdominal discomfort
  8. Acute pulmonary oedema (sudden deposit of fluid in the lung))
  9. Asthenia (weakness)
  10. Brain natriuretic peptide increased

What are the existing conditions these people have? *

  1. Chest Pain: 4 people, 18.18%
  2. Sleep Disorder: 3 people, 13.64%
  3. Pain: 3 people, 13.64%
  4. Wheezing (a high-pitched whistling sound made while you breath): 2 people, 9.09%
  5. Nausea (feeling of having an urge to vomit): 2 people, 9.09%
  6. Malignant Melanoma (skin cancer rises from melancytes): 2 people, 9.09%
  7. Dyspnea (difficult or laboured breathing): 2 people, 9.09%
  8. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Multaq and Prinivil?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Multaq and Prinivil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Multaq:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Prinivil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Multaq and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prinivil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on dronedarone hydrochloride and lisinopril (the active ingredients of Multaq and Prinivil, respectively), and Multaq and Prinivil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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