Multaq and Trelegy ellipta drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Multaq (dronedarone hydrochloride) and Trelegy ellipta (fluticasone furoate; umeclidinium bromide; vilanterol trifenatate). Common drug interactions include pain among females and death among males.
The phase IV clinical study analyzes what interactions people have when they take Multaq and Trelegy ellipta. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.
What is Multaq?
Multaq has active ingredients of dronedarone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 11,053 Multaq users. Check the latest studies of Multaq.
What is Trelegy ellipta?
Trelegy ellipta has active ingredients of fluticasone furoate; umeclidinium bromide; vilanterol trifenatate. eHealthMe is studying from 28,101 Trelegy ellipta users. Check the latest studies of Trelegy ellipta.
16 people who take Multaq and Trelegy ellipta together, and have interactions are studied.

What are the common drug interactions of Multaq and Trelegy Ellipta, by gender? *:
female:
- Pain
- Arthralgia (joint pain)
- Asthma
- Back pain
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Fatigue (feeling of tiredness)
- Headache (pain in head)
- Infusion related reaction
- Lower respiratory tract infection
- Nasopharyngitis (inflammation of the nasopharynx)
male:
- Death
- Arthralgia (joint pain)
- Wheezing (a high-pitched whistling sound made while you breath)
- Back pain
- Cough
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
- Hypoacusis (loss of hearing)
- Productive cough
- Squamous cell carcinoma of skin (a cancer of a kind of epithelial cell, the squamous cell. these cells are the main part of the epidermis of the skin)
What are the common drug interactions of Multaq and Trelegy Ellipta, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Chronic kidney disease
- Death
- Urinary tract infection
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Renal failure (kidney dysfunction)
- Biliary colic
- Dyspnoea (difficult or laboured respiration)
- Haemoglobin decreased
What are the existing conditions these people have? *
- Immunodeficiency Common Variable: 4 people, 25.00%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 18.75%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 12.50%
- Multiple Myeloma (cancer of the plasma cells): 2 people, 12.50%
- Wheezing (a high-pitched whistling sound made while you breath): 1 person, 6.25%
- Asthma: 1 person, 6.25%
- Back Pain: 1 person, 6.25%
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 1 person, 6.25%
- Coronary Heart Disease (narrowing or blockage of the coronary arteries): 1 person, 6.25%
- Cough: 1 person, 6.25%
* Approximation only. Some reports may have incomplete information.
Do you take Multaq and Trelegy ellipta?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Multaq (11,053 reports)
- Trelegy ellipta (28,101 reports)
Browse all drug interactions of Multaq and Trelegy ellipta:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Multaq:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Trelegy ellipta:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Multaq and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Trelegy ellipta and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on dronedarone hydrochloride and fluticasone furoate; umeclidinium bromide; vilanterol trifenatate (the active ingredients of Multaq and Trelegy ellipta, respectively), and Multaq and Trelegy ellipta (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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