Multihance and Fluoxetine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Multihance (gadobenate dimeglumine) and Fluoxetine (fluoxetine hydrochloride). Common drug interactions include fibrosis among females and emotional distress among males.

The phase IV clinical study analyzes what interactions people have when they take Multihance and Fluoxetine. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Multihance?

Multihance has active ingredients of gadobenate dimeglumine. eHealthMe is studying from 5,786 Multihance users. Check the latest studies of Multihance.

What is Fluoxetine?

Fluoxetine has active ingredients of fluoxetine hydrochloride. It is often used in depression. eHealthMe is studying from 98,824 Fluoxetine users. Check the latest studies of Fluoxetine.



On Aug, 02, 2026

21 people who take Multihance and Fluoxetine together, and have interactions are studied.

Multihance and Fluoxetine drug interactions.

What are the common drug interactions of Multihance and Fluoxetine, by gender? *:

female:

  1. Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
  2. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  3. Pain
  4. General physical health deterioration (weak health status)
  5. Scar
  6. Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
  7. Joint range of motion decreased (disease of joint movement)
  8. Oedema peripheral (superficial swelling)
  9. Pruritus (severe itching of the skin)
  10. Skin induration (an abnormally hard spot or area on the skin)

male:

  1. Emotional distress
  2. Joint range of motion decreased (disease of joint movement)
  3. Skin fibrosis (fibrous tissue formation on skin)
  4. Skin hypertrophy (skin cells enlarges)
  5. Skin induration (an abnormally hard spot or area on the skin)
  6. Skin tightness
  7. Mobility decreased (ability to move is reduced)
  8. Muscular weakness (muscle weakness)
  9. Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
  10. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)

What are the common drug interactions of Multihance and Fluoxetine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Anaphylactoid reaction (type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation)

30-39:

  1. Anaphylactic reaction (serious allergic reaction)

40-49:

  1. Hypersensitivity

50-59:

  1. Burning sensation
  2. Contrast media allergy (reaction associated with the use of intravenous contrast material during radiology)
  3. Deformity (disfigurement)
  4. Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
  5. General physical health deterioration (weak health status)
  6. Joint contracture (a permanent shortening of a muscle or joint)
  7. Joint range of motion decreased (disease of joint movement)
  8. Joint stiffness
  9. Joint swelling
  10. Mobility decreased (ability to move is reduced)

60+:

  1. Syncope (loss of consciousness with an inability to maintain postural tone)
  2. Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
  3. Gait disturbance
  4. Induration (thickening of tissue)
  5. Injury
  6. Mobility decreased (ability to move is reduced)
  7. Muscular weakness (muscle weakness)
  8. Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
  9. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  10. Myosclerosis (hardening of muscle tissue)

What are the existing conditions these people have? *

  1. Nuclear Magnetic Resonance Imaging Abdominal: 4 people, 19.05%
  2. Computerised Tomogram Abdomen: 4 people, 19.05%
  3. Nuclear Magnetic Resonance Imaging Brain: 2 people, 9.52%
  4. Adverse Event: 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

Do you take Multihance and Fluoxetine?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Multihance and Fluoxetine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Multihance:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Fluoxetine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Multihance and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Fluoxetine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on gadobenate dimeglumine and fluoxetine hydrochloride (the active ingredients of Multihance and Fluoxetine, respectively), and Multihance and Fluoxetine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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