Multihance and Voltaren drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Multihance (gadobenate dimeglumine) and Voltaren (diclofenac sodium). Common drug interactions include nephrogenic systemic fibrosis among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Multihance and Voltaren. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Multihance?

Multihance has active ingredients of gadobenate dimeglumine. eHealthMe is studying from 5,786 Multihance users. Check the latest studies of Multihance.

What is Voltaren?

Voltaren has active ingredients of diclofenac sodium. It is often used in arthritis. eHealthMe is studying from 82,346 Voltaren users. Check the latest studies of Voltaren.



On Jul, 28, 2026

13 people who take Multihance and Voltaren together, and have interactions are studied.

Multihance and Voltaren drug interactions.

What are the common drug interactions of Multihance and Voltaren, by gender? *:

female:

  1. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  2. Skin fibrosis (fibrous tissue formation on skin)
  3. Activities of daily living impaired
  4. Arthralgia (joint pain)
  5. Asthenia (weakness)
  6. Back pain
  7. Burning sensation
  8. Deformity (disfigurement)
  9. Groin pain
  10. Hypoaesthesia (reduced sense of touch or sensation)

male:

  1. Arthralgia (joint pain)
  2. Back pain
  3. Stress
  4. Extremity contracture (permanent shortening of a muscle or joint of arms and legs)
  5. Fall
  6. Joint lock
  7. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  8. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  9. Peroneal nerve palsy
  10. Vascular calcification (deposits of calcium in the blood vessels)

What are the common drug interactions of Multihance and Voltaren, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Arthralgia (joint pain)
  2. Back pain
  3. Extremity contracture (permanent shortening of a muscle or joint of arms and legs)
  4. Fall
  5. Joint lock
  6. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  7. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  8. Peroneal nerve palsy
  9. Vascular calcification (deposits of calcium in the blood vessels)
  10. Quality of life decreased

30-39:

n/a

40-49:

n/a

50-59:

  1. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  2. Skin fibrosis (fibrous tissue formation on skin)
  3. Joint range of motion decreased (disease of joint movement)
  4. Muscle tightness
  5. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  6. Oedema peripheral (superficial swelling)
  7. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  8. Pruritus generalised (generalized itching)
  9. Skin discolouration (change of skin colour)
  10. Skin hypertrophy (skin cells enlarges)

60+:

n/a

What are the existing conditions these people have? *

  1. Asthma: 7 people, 53.85%
  2. Nuclear Magnetic Resonance Imaging Brain: 3 people, 23.08%
  3. Tumor: 2 people, 15.38%
  4. Thyroid Cancer: 2 people, 15.38%
  5. Pain: 2 people, 15.38%
  6. Oedema Peripheral (superficial swelling): 2 people, 15.38%
  7. Joint Swelling: 2 people, 15.38%
  8. Depression: 2 people, 15.38%
  9. Blood Pressure Abnormal: 2 people, 15.38%
  10. Back Pain: 2 people, 15.38%

* Approximation only. Some reports may have incomplete information.

Do you take Multihance and Voltaren?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Multihance and Voltaren:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Multihance:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Voltaren:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Multihance and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Voltaren and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on gadobenate dimeglumine and diclofenac sodium (the active ingredients of Multihance and Voltaren, respectively), and Multihance and Voltaren (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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