Multivitamin and Zyflo drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Multivitamin (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e) and Zyflo (zileuton). Common drug interactions include sinusitis among females and musculoskeletal chest pain among males.
The phase IV clinical study analyzes what interactions people have when they take Multivitamin and Zyflo. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.
What is Multivitamin?
Multivitamin has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 83,598 Multivitamin users. Check the latest studies of Multivitamin.
What is Zyflo?
Zyflo has active ingredients of zileuton. eHealthMe is studying from 1,004 Zyflo users. Check the latest studies of Zyflo.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
18 people who take Multivitamin and Zyflo together, and have interactions are studied.

What are the common drug interactions of Multivitamin and Zyflo, by gender? *:
female:
- Sinusitis (inflammation of sinus)
- Arthralgia (joint pain)
- Blood pressure decreased
- Dizziness
- Migraine (headache)
- Fatigue (feeling of tiredness)
- Asthma
- Bedridden
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Cough
male:
- Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
- Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
- Adverse drug reaction
- Delusion (a false belief or opinion)
- Hallucination (an experience involving the perception of something not present)
- Hypersomnia (excessive daytime sleepiness (eds))
- Lethargy (tiredness)
- Memory impairment
- Somnolence (a state of near-sleep, a strong desire for sleep)
What are the common drug interactions of Multivitamin and Zyflo, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Arthralgia (joint pain)
- Asthma
- Cough
- Dyspnoea (difficult or laboured respiration)
- Ear pain
- Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
- Headache (pain in head)
- Injection site pain
- Migraine (headache)
- Muscular weakness (muscle weakness)
30-39:
n/a
40-49:
n/a
50-59:
- Fatigue (feeling of tiredness)
- Headache (pain in head)
- Sinusitis (inflammation of sinus)
- Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
- Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
- Rash papular (redness with papule)
- Urticaria (rash of round, red welts on the skin that itch intensely)
60+:
- Adverse drug reaction
- Arthralgia (joint pain)
- Lethargy (tiredness)
- Lung disorder (lung disease)
- Memory impairment
- Migraine (headache)
- Pneumonia
- Rectal fissure (painful condition in which a cut or tear occurs in the anus)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Bedridden
What are the existing conditions these people have? *
- Asthma: 4 people, 22.22%
- Parkinson's Disease: 4 people, 22.22%
- Pulmonary Hypertension (increase in blood pressure in the lung artery): 2 people, 11.11%
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 11.11%
- Portal Hypertension (increase in the blood pressure within a system of veins called the portal venous system): 2 people, 11.11%
- Immunodeficiency Common Variable: 2 people, 11.11%
- Hypoglobulinaemia (deficiency of globulin in the bloodstream): 2 people, 11.11%
- Fibrosis (formation of excess fibrous connective tissue in an organ or tissue): 2 people, 11.11%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.56%
- Blood Potassium Decreased: 1 person, 5.56%
* Approximation only. Some reports may have incomplete information.
Do you take Multivitamin and Zyflo?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Multivitamin (83,598 reports)
- Zyflo (1,004 reports)
Browse all drug interactions of Multivitamin and Zyflo:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Multivitamin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Zyflo:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Multivitamin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zyflo and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e and zileuton (the active ingredients of Multivitamin and Zyflo, respectively), and Multivitamin and Zyflo (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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