Mupirocin and Leflunomide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mupirocin (mupirocin) and Leflunomide (leflunomide). Common drug interactions include blood glucose decreased among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Mupirocin and Leflunomide. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.

What is Mupirocin?

Mupirocin has active ingredients of mupirocin. It is often used in impetigo. eHealthMe is studying from 5,940 Mupirocin users. Check the latest studies of Mupirocin.

What is Leflunomide?

Leflunomide has active ingredients of leflunomide. It is often used in rheumatoid arthritis. eHealthMe is studying from 82,105 Leflunomide users. Check the latest studies of Leflunomide.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 21, 2026

45 people who take Mupirocin and Leflunomide together, and have interactions are studied.

Mupirocin and Leflunomide drug interactions.

What are the common drug interactions of Mupirocin and Leflunomide, by gender? *:

female:

Blood glucose decreased
Chronic kidney disease
Depressed mood
Epicondylitis (tennis elbow)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Immunodeficiency
Mood swings (an extreme or rapid change in mood)
Osteoporosis (bones weak and more likely to break)
Postural reflex impairment
Restlessness (not able to rest)

male:

Arthralgia (joint pain)
Asthenia (weakness)
Parkinson's disease
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)
Respiratory tract congestion (blockage on respiratory system)
Skin infection
Weight decreased
Dizziness
Headache (pain in head)

What are the common drug interactions of Mupirocin and Leflunomide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Subcutaneous abscess

20-29:

n/a

30-39:

Rash
Abdominal discomfort
Alopecia (absence of hair from areas of the body)
Cough
Dactylitis (dactylitis or sausage digit is inflammation of an entire digit (a finger or toe), and can be painful)
Dyspnoea (difficult or laboured respiration)
Enthesopathy (disorder of entheses (bone attachments))
Psoriasis (immune-mediated disease that affects the skin)
Rectal haemorrhage (bleeding from anus)
Spinal osteoarthritis (joint cartilage loss in spine)

40-49:

Pain
Uterine haemorrhage (uterine bleeding)
Arthralgia (joint pain)
Drug ineffective
Precancerous skin lesion
Skin cancer

50-59:

Stress
Drug ineffective
Joint swelling
Arthralgia (joint pain)
Back pain
Dry skin
Emotional distress
Hyperkeratosis (thickening of the outer layer of the skin)
Knee arthroplasty
Koilonychia (soft nails that look scooped out in anaemia)

60+:

Asthenia (weakness)
Cardiac disorder
Lung disorder (lung disease)
Obstruction
Parkinson's disease
Renal impairment (severely reduced kidney function)
Respiratory tract congestion (blockage on respiratory system)
Skin infection
Arthralgia (joint pain)
Dizziness

What are the existing conditions these people have? *

Arthritis (form of joint disorder that involves inflammation of one or more joints): 11 people, 24.44%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 8 people, 17.78%
Immunodeficiency Common Variable: 7 people, 15.56%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 6 people, 13.33%
Bone Density Abnormal: 6 people, 13.33%
Psoriasis (immune-mediated disease that affects the skin): 4 people, 8.89%
Osteoporosis (bones weak and more likely to break): 4 people, 8.89%

* Approximation only. Some reports may have incomplete information.

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