Mysoline and Acyclovir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mysoline (primidone) and Acyclovir (acyclovir). Common drug interactions include deafness transitory among females and infection among males.

The phase IV clinical study analyzes what interactions people have when they take Mysoline and Acyclovir. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Mysoline?

Mysoline has active ingredients of primidone. It is often used in essential tremor. eHealthMe is studying from 2,849 Mysoline users. Check the latest studies of Mysoline.

What is Acyclovir?

Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,961 Acyclovir users. Check the latest studies of Acyclovir.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 21, 2026

27 people who take Mysoline and Acyclovir together, and have interactions are studied.

Mysoline and Acyclovir drug interactions.

What are the common drug interactions of Mysoline and Acyclovir, by gender? *:

female:

Deafness transitory (deafness temporary)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dyspnoea (difficult or laboured respiration)
Erythema (redness of the skin)
Haematocrit decreased
Local swelling (swelling at the site of some application of substance or injury)
Pneumonia viral
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
Dehydration (dryness resulting from the removal of water)
Febrile neutropenia (fever with reduced white blood cells)

male:

Infection
Anaemia (lack of blood)
Hepatomegaly (abnormal enlargement of the liver)
Injury
Osteitis (a general term for inflammation of bone)
Pain
Skin lesion
Swelling
Tooth abscess (pus formation in tooth)
Cellulitis (infection under the skin)

What are the common drug interactions of Mysoline and Acyclovir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Dizziness
Haemorrhage (bleeding)
Head injury
Abnormal behaviour
Developmental delay
Hepatitis c
Tremor (trembling or shaking movements in one or more parts of your body)
Confusion
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Anxiety
Anaemia (lack of blood)
Infection
Injury
Osteitis (a general term for inflammation of bone)
Pain
Skin lesion
Swelling
Tooth abscess (pus formation in tooth)
Cellulitis (infection under the skin)

What are the existing conditions these people have? *

Pain: 7 people, 25.93%
Multiple Myeloma (cancer of the plasma cells): 4 people, 14.81%
Osteoporosis (bones weak and more likely to break): 3 people, 11.11%
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream): 2 people, 7.41%
Hiv Infection: 2 people, 7.41%
Blood Iron Decreased: 2 people, 7.41%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 7.41%
Dehydration (dryness resulting from the removal of water): 2 people, 7.41%
Depression: 2 people, 7.41%
Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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