Nabumetone and Ranexa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nabumetone (nabumetone) and Ranexa (ranolazine). Common drug interactions include chronic kidney disease among females and hallucination among males.

The phase IV clinical study analyzes what interactions people have when they take Nabumetone and Ranexa. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Nabumetone?

Nabumetone has active ingredients of nabumetone. It is often used in arthritis. eHealthMe is studying from 9,554 Nabumetone users. Check the latest studies of Nabumetone.

What is Ranexa?

Ranexa has active ingredients of ranolazine. It is often used in angina. eHealthMe is studying from 11,758 Ranexa users. Check the latest studies of Ranexa.



On Jul, 20, 2026

18 people who take Nabumetone and Ranexa together, and have interactions are studied.

Nabumetone and Ranexa drug interactions.

What are the common drug interactions of Nabumetone and Ranexa, by gender? *:

female:

  1. Chronic kidney disease
  2. Age-related macular degeneration
  3. Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest)
  4. Psoriasis (immune-mediated disease that affects the skin)
  5. Renal failure (kidney dysfunction)
  6. Renal injury (kidney injury)
  7. Asthenia (weakness)
  8. Balance disorder
  9. Blood calcium increased
  10. Blood parathyroid hormone increased

male:

  1. Hallucination (an experience involving the perception of something not present)
  2. Abdominal discomfort
  3. Neuropathy peripheral (surface nerve damage)
  4. Platelet count decreased
  5. Tibia fracture (fracture of lower leg bone)
  6. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  7. Burning sensation
  8. Chronic kidney disease
  9. Drug hypersensitivity
  10. Dyspnoea (difficult or laboured respiration)

What are the common drug interactions of Nabumetone and Ranexa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Renal injury (kidney injury)

50-59:

  1. Age-related macular degeneration
  2. Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest)
  3. Psoriasis (immune-mediated disease that affects the skin)

60+:

  1. Chronic kidney disease
  2. Hallucination (an experience involving the perception of something not present)
  3. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  4. Abdominal discomfort
  5. Dyspnoea (difficult or laboured respiration)
  6. Fatigue (feeling of tiredness)
  7. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  8. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  9. Platelet count decreased
  10. Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 22.22%
  2. Indigestion: 3 people, 16.67%
  3. Stress And Anxiety: 3 people, 16.67%
  4. High Blood Pressure: 3 people, 16.67%
  5. Infection: 2 people, 11.11%
  6. Urinary Tract Infection: 2 people, 11.11%
  7. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 11.11%
  8. Hypersensitivity: 2 people, 11.11%
  9. High Blood Cholesterol: 2 people, 11.11%
  10. Fluid Retention (an abnormal accumulation of fluid in the blood): 2 people, 11.11%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Nabumetone and Ranexa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nabumetone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ranexa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nabumetone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ranexa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on nabumetone and ranolazine (the active ingredients of Nabumetone and Ranexa, respectively), and Nabumetone and Ranexa (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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