Naloxone and Lactobacillus drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Naloxone (naloxone hydrochloride) and Lactobacillus (lactobacillus). Common drug interactions include acute respiratory failure among females and alcohol abuse among males.

The phase IV clinical study analyzes what interactions people have when they take Naloxone and Lactobacillus. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Naloxone?

Naloxone has active ingredients of naloxone hydrochloride. eHealthMe is studying from 6,425 Naloxone users. Check the latest studies of Naloxone.

What is Lactobacillus?

Lactobacillus has active ingredients of lactobacillus. It is often used in stomach discomfort. eHealthMe is studying from 5,854 Lactobacillus users. Check the latest studies of Lactobacillus.

On Aug, 11, 2026

18 people who take Naloxone and Lactobacillus together, and have interactions are studied.

Naloxone and Lactobacillus drug interactions.

What are the common drug interactions of Naloxone and Lactobacillus, by gender? *:

female:

Acute respiratory failure
Blood creatinine increased
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Cellulitis (infection under the skin)
Chronic kidney disease
Death
Essential hypertension (primary hypertension)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)

male:

Alcohol abuse
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hypotension (abnormally low blood pressure)
Joint effusion (presence of extra fluid in joint covering)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Ventricular fibrillation (abnormally irregular heart rhythm)
Lung abscess (pus in lungs)
Pneumonia
Respiratory failure (inadequate gas exchange by the respiratory system)
Staphylococcal sepsis (blood infection by an infection with staphylococcus bacteria)

What are the common drug interactions of Naloxone and Lactobacillus, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Procedural pain

10-19:

Drug withdrawal convulsions
Pneumonia
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

20-29:

n/a

30-39:

n/a

40-49:

Alcohol abuse
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Lung abscess (pus in lungs)

50-59:

Blood creatinine increased
Cardiac arrest
Chronic kidney disease
Essential hypertension (primary hypertension)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Hypotension (abnormally low blood pressure)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)

60+:

Cellulitis (infection under the skin)
Pneumonia
Respiratory failure (inadequate gas exchange by the respiratory system)
Staphylococcal sepsis (blood infection by an infection with staphylococcus bacteria)
Acute respiratory failure
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Death
Febrile neutropenia (fever with reduced white blood cells)
Joint effusion (presence of extra fluid in joint covering)

What are the existing conditions these people have? *

Pain: 4 people, 22.22%
Thrombocytopenia (decrease of platelets in blood): 1 person, 5.56%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 5.56%
Blood Glucose Increased: 1 person, 5.56%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 5.56%
Chronic Myelomonocytic Leukaemia (cancers of the blood-forming cells of the bone marrow): 1 person, 5.56%
Constipation: 1 person, 5.56%
Cystic Fibrosis (disease of the secretary glands): 1 person, 5.56%
Encephalitis (inflammation of the brain): 1 person, 5.56%
Encephalomyelitis (inflammation of the brain and spinal cord): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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