Naloxone and Thalidomide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Naloxone (naloxone hydrochloride) and Thalidomide (thalidomide). Common drug interactions include atrial fibrillation among females and acute generalised exanthematous pustulosis among males.

The phase IV clinical study analyzes what interactions people have when they take Naloxone and Thalidomide. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Naloxone?

Naloxone has active ingredients of naloxone hydrochloride. eHealthMe is studying from 6,425 Naloxone users. Check the latest studies of Naloxone.

What is Thalidomide?

Thalidomide has active ingredients of thalidomide. eHealthMe is studying from 16,473 Thalidomide users. Check the latest studies of Thalidomide.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

33 people who take Naloxone and Thalidomide together, and have interactions are studied.

Naloxone and Thalidomide drug interactions.

What are the common drug interactions of Naloxone and Thalidomide, by gender? *:

female:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Fall
Unresponsive to stimuli
Abdominal discomfort
Abdominal mass (localized enlargement or swelling in the human abdomen)
Abscess soft tissue (soft tissue abscesses)
Acquired oesophageal web (structural abnormalities in the oesophagus)
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Alveolar osteitis (complication of wound healing following extraction of a tooth)
Anaemia (lack of blood)

male:

Acute generalised exanthematous pustulosis (acute febrile drug eruption)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Candidiasis (candidiasis or thrush is a fungal infection)
Cardiomyopathy (weakening of the heart muscle)
Cyst (a closed sac)
Cytomegalovirus infection
Decreased interest
Dehydration (dryness resulting from the removal of water)
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)

What are the common drug interactions of Naloxone and Thalidomide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Ewing's sarcoma (malignant small, round, blue cell tumour)

20-29:

n/a

30-39:

n/a

40-49:

Anaemia (lack of blood)
Anxiety
Arthralgia (joint pain)
Asthenia (weakness)
Blood magnesium decreased
Blood sodium decreased
Bone disorder
Bone marrow disorder
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)

50-59:

n/a

60+:

Acute generalised exanthematous pustulosis (acute febrile drug eruption)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Haemoglobin decreased
Haematocrit decreased
Oropharyngeal pain
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Pharyngitis (inflammation of the pharynx, causing a sore throat)
Pustular psoriasis (raised bumps on the skin that are filled with pus)
White blood cell count decreased
Respiratory failure (inadequate gas exchange by the respiratory system)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 10 people, 30.30%
Stress And Anxiety: 2 people, 6.06%
Pain: 2 people, 6.06%
Constipation: 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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