Naltrexone and Heparin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Naltrexone (naltrexone) and Heparin (heparin sodium). Common drug interactions include metastases to bone among females and autoimmune disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Naltrexone and Heparin. It is created by eHealthMe based on reports of 78 people who take the same drugs from the FDA, and is updated regularly.

What is Naltrexone?

Naltrexone has active ingredients of naltrexone. eHealthMe is studying from 4,833 Naltrexone users. Check the latest studies of Naltrexone.

What is Heparin?

Heparin has active ingredients of heparin sodium. It is often used in blood clots. eHealthMe is studying from 92,141 Heparin users. Check the latest studies of Heparin.



On Jul, 27, 2026

78 people who take Naltrexone and Heparin together, and have interactions are studied.

Naltrexone and Heparin drug interactions.

What are the common drug interactions of Naltrexone and Heparin, by gender? *:

female:

  1. Metastases to bone (cancer spreads to bone)
  2. Metastases to liver (cancer spreads to liver)
  3. Pancreatic carcinoma (pancreatic cancer)
  4. Skin disorder (skin disease)
  5. Skin mass
  6. Ulcer
  7. Urinary incontinence (inability to control the flow of urine and involuntary urination)
  8. Vaginal cancer
  9. Vaginal haemorrhage (vaginal bleeding)
  10. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)

male:

  1. Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
  2. Bartonellosis (infectious disease produced by bacteria of the genus bartonella)
  3. Viral infection
  4. Abdominal distension
  5. Babesiosis (malaria-like parasitic disease caused by infection with babesia)
  6. Device dislocation
  7. Laryngitis (inflammation of the larynx)
  8. Sinusitis (inflammation of sinus)
  9. Umbilical hernia (an outward bulging (protrusion) of the abdominal lining or part of the abdominal organ(s) through the area around the belly button)
  10. Weight gain poor

What are the common drug interactions of Naltrexone and Heparin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
  2. Bartonellosis (infectious disease produced by bacteria of the genus bartonella)
  3. Dark circles under eyes
  4. Lyme disease (a bacterial infection that is spread to humans by infected ticks)
  5. Malaise (a feeling of general discomfort or uneasiness)
  6. Migraine (headache)
  7. Mycotic allergy (fungal allergy)
  8. Vomiting
  9. Fungal infection
  10. Device dislocation

10-19:

  1. Abdominal distension
  2. Laryngitis (inflammation of the larynx)
  3. Sinusitis (inflammation of sinus)
  4. Abdominal pain
  5. Anxiety
  6. Bacterial infection
  7. Bartonellosis (infectious disease produced by bacteria of the genus bartonella)
  8. Dehydration (dryness resulting from the removal of water)
  9. Depression
  10. Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)

20-29:

n/a

30-39:

  1. Injection site pain
  2. Pain
  3. Physical product label issue
  4. Pruritus (severe itching of the skin)
  5. Staphylococcal infection (an infection with staphylococcus bacteria)
  6. Swelling
  7. Tenderness (pain or discomfort when an affected area is touched)
  8. Urticaria (rash of round, red welts on the skin that itch intensely)
  9. Weight increased
  10. Fatigue (feeling of tiredness)

40-49:

  1. Arthralgia (joint pain)
  2. Asthma
  3. Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
  4. Device occlusion
  5. Dizziness
  6. Ear congestion
  7. Fall
  8. Fatigue (feeling of tiredness)
  9. Headache (pain in head)
  10. Hereditary angioedema (recurrent episodes of severe swelling)

50-59:

  1. Abdominal discomfort
  2. Gastrointestinal infection (infection of stomach and intestine)
  3. Urinary tract infection
  4. Abdominal pain
  5. Arthralgia (joint pain)
  6. Blepharospasm (any abnormal contraction or twitch of the eyelid)
  7. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  8. Cellulitis (infection under the skin)
  9. Dehydration (dryness resulting from the removal of water)
  10. Duodenal obstruction (partial or complete obstruction of the duodenum)

60+:

  1. Chronic kidney disease
  2. Hyperkalaemia (damage to or disease of the kidney)
  3. Lip swelling
  4. Metal poisoning
  5. Multiple allergies (allergy to multiple agents)
  6. Muscle spasms (muscle contraction)
  7. Nasopharyngitis (inflammation of the nasopharynx)
  8. Oral herpes (viral infection of mouth)
  9. Oropharyngeal pain
  10. Productive cough

What are the existing conditions these people have? *

  1. Immunodeficiency Common Variable: 33 people, 42.31%
  2. Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously): 7 people, 8.97%
  3. Nervous System Disorder (a general class of medical conditions affecting the nervous system): 7 people, 8.97%
  4. Immune System Disorder: 7 people, 8.97%
  5. Autonomic Neuropathy (malfunction of the autonomic nervous system (ans)): 7 people, 8.97%
  6. Pain: 6 people, 7.69%
  7. B-Lymphocyte Abnormalities (abnormal population of b lymphocytes in the blood, bone marrow, or tissues): 6 people, 7.69%
  8. Primary Immunodeficiency Syndrome: 5 people, 6.41%
  9. Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 5 people, 6.41%
  10. Hereditary Angioedema (recurrent episodes of severe swelling): 5 people, 6.41%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Naltrexone and Heparin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Naltrexone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Heparin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Naltrexone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Heparin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on naltrexone and heparin sodium (the active ingredients of Naltrexone and Heparin, respectively), and Naltrexone and Heparin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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