Naprosyn and Bisacodyl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Naprosyn (naproxen) and Bisacodyl (bisacodyl). Common drug interactions include bone disorder among females and multiple injuries among males.

The phase IV clinical study analyzes what interactions people have when they take Naprosyn and Bisacodyl. It is created by eHealthMe based on reports of 69 people who take the same drugs from the FDA, and is updated regularly.

What is Naprosyn?

Naprosyn has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 16,738 Naprosyn users. Check the latest studies of Naprosyn.

What is Bisacodyl?

Bisacodyl has active ingredients of bisacodyl. It is often used in constipation. eHealthMe is studying from 18,852 Bisacodyl users. Check the latest studies of Bisacodyl.



On Jul, 11, 2026

69 people who take Naprosyn and Bisacodyl together, and have interactions are studied.

Naprosyn and Bisacodyl drug interactions.

What are the common drug interactions of Naprosyn and Bisacodyl, by gender? *:

female:

  1. Bone disorder
  2. Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
  3. Hypoaesthesia (reduced sense of touch or sensation)
  4. Pain in jaw
  5. Malignant neoplasm progression (cancer tumour came back)
  6. Tooth extraction
  7. Oedema peripheral (superficial swelling)
  8. Osteonecrosis of jaw (death of bone of jaw)
  9. Fatigue (feeling of tiredness)
  10. Intervertebral disc degeneration (spinal disc degeneration)

male:

  1. Multiple injuries
  2. Haemorrhagic stroke (stroke caused by the rupture of a blood vessel in the brain)
  3. Pupils unequal
  4. Skin necrosis (skin damage)
  5. Wound infection
  6. Anxiety
  7. Chronic kidney disease
  8. Nausea (feeling of having an urge to vomit)
  9. Vomiting
  10. Diarrhoea

What are the common drug interactions of Naprosyn and Bisacodyl, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Thrombophlebitis superficial (swelling (inflammation) of a superficial vein caused by a blood clot)

30-39:

  1. Arthralgia (joint pain)
  2. Leiomyoma (a noncancerous (benign) tumour made up mostly of smooth muscle cells)
  3. Abdominal pain
  4. Anxiety
  5. Bipolar disorder (mood disorder)
  6. Blood cholesterol increased
  7. Bone density decreased
  8. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  9. Burning sensation
  10. Chronic kidney disease

40-49:

  1. Oedema peripheral (superficial swelling)
  2. Abdominal pain
  3. Anaemia (lack of blood)
  4. Chest pain
  5. Acute sinusitis
  6. Arteriosclerosis (thickening and hardening of arteries)
  7. Blood cholesterol increased
  8. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  9. Cardiac murmur (an heart sound in valve abnormality)
  10. Cerebral arteriosclerosis (thickening and hardening of the walls of the arteries in the brain)

50-59:

  1. Vomiting
  2. Weight decreased
  3. Malignant neoplasm progression (cancer tumour came back)
  4. Tooth extraction
  5. Intervertebral disc degeneration (spinal disc degeneration)
  6. Osteonecrosis of jaw (death of bone of jaw)
  7. Hydronephrosis (water inside the kidney)
  8. Intervertebral disc protrusion (spinal disc protrusion)
  9. Diarrhoea
  10. Alopecia (absence of hair from areas of the body)

60+:

  1. Leukocytosis (increased white blood cells)
  2. Septic shock (shock due to blood infection)
  3. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  4. Fatigue (feeling of tiredness)
  5. Loss of consciousness
  6. Nausea (feeling of having an urge to vomit)
  7. Pneumonia
  8. Protein c deficiency
  9. Skin necrosis (skin damage)
  10. Urinary tract infection

What are the existing conditions these people have? *

  1. Metastases To Bone (cancer spreads to bone): 18 people, 26.09%
  2. Breast Cancer: 17 people, 24.64%
  3. Depression: 17 people, 24.64%
  4. High Blood Pressure: 17 people, 24.64%
  5. Muscle Spasms (muscle contraction): 14 people, 20.29%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 17.39%
  7. Stress And Anxiety: 11 people, 15.94%
  8. Arthritis (form of joint disorder that involves inflammation of one or more joints): 10 people, 14.49%
  9. Bone Pain: 9 people, 13.04%
  10. Breast Cancer Metastatic: 8 people, 11.59%

* Approximation only. Some reports may have incomplete information.

Do you take Naprosyn and Bisacodyl?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Naprosyn and Bisacodyl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Naprosyn:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Bisacodyl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Naprosyn and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bisacodyl and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on naproxen and bisacodyl (the active ingredients of Naprosyn and Bisacodyl, respectively), and Naprosyn and Bisacodyl (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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