Naprosyn and Donepezil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Naprosyn (naproxen) and Donepezil (donepezil hydrochloride). Common drug interactions include intestinal ischaemia among females and hallucination among males.

The phase IV clinical study analyzes what interactions people have when they take Naprosyn and Donepezil. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Naprosyn?

Naprosyn has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 16,738 Naprosyn users. Check the latest studies of Naprosyn.

What is Donepezil?

Donepezil has active ingredients of donepezil hydrochloride. It is often used in dementia. eHealthMe is studying from 24,564 Donepezil users. Check the latest studies of Donepezil.

On Jul, 08, 2026

18 people who take Naprosyn and Donepezil together, and have interactions are studied.

Naprosyn and Donepezil drug interactions.

What are the common drug interactions of Naprosyn and Donepezil, by gender? *:

female:

Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)

male:

Hallucination (an experience involving the perception of something not present)
Nightmare (unpleasant dream)
Haematemesis (vomiting of blood)
Melaena (the passage of black, tarry stools)
Death
Mood swings (an extreme or rapid change in mood)
Photosensitivity reaction
Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)

What are the common drug interactions of Naprosyn and Donepezil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Hallucination (an experience involving the perception of something not present)
Nightmare (unpleasant dream)
Haematemesis (vomiting of blood)
Melaena (the passage of black, tarry stools)
Death
Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 11.11%
Gait Disturbance: 2 people, 11.11%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 1 person, 5.56%
Memory Loss: 1 person, 5.56%
Idiopathic Pulmonary Fibrosis (chronic lung disease): 1 person, 5.56%
Cushing's Syndrome (obesity, a rounded face, increased fat): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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