Naprosyn and Halcion drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Naprosyn (naproxen) and Halcion (triazolam). Common drug interactions include gastrointestinal haemorrhage among females and abnormal faeces among males.

The phase IV clinical study analyzes what interactions people have when they take Naprosyn and Halcion. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Naprosyn?

Naprosyn has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 16,738 Naprosyn users. Check the latest studies of Naprosyn.

What is Halcion?

Halcion has active ingredients of triazolam. It is often used in insomnia. eHealthMe is studying from 8,268 Halcion users. Check the latest studies of Halcion.



On Jul, 13, 2026

12 people who take Naprosyn and Halcion together, and have interactions are studied.

Naprosyn and Halcion drug interactions.

What are the common drug interactions of Naprosyn and Halcion, by gender? *:

female:

  1. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  2. Death
  3. Haemorrhage (bleeding)
  4. Ulcer haemorrhage (bleeding ulcer)
  5. Anxiety
  6. Colonic stenosis (abnormal narrowing of colon)
  7. Depression
  8. Drug dependence
  9. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  10. Fall

male:

  1. Abnormal faeces (abnormal stool)
  2. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  3. Electrocardiogram abnormal
  4. Fear
  5. Hemiplegia (paralysis of one side of the body)
  6. Hypercholesterolaemia (high levels of cholesterol in the blood)
  7. Injury
  8. Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
  9. Migraine (headache)
  10. Nervous system disorder (a general class of medical conditions affecting the nervous system)

What are the common drug interactions of Naprosyn and Halcion, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Colonic stenosis (abnormal narrowing of colon)
  2. Depression
  3. General physical health deterioration (weak health status)
  4. Osteonecrosis (death of bone)
  5. Back disorder
  6. Blood thyroid stimulating hormone increased
  7. Cartilage injury
  8. Cellulitis (infection under the skin)
  9. Cholangitis sclerosing (infection and obstruction of bile duct)
  10. Chondropathy (disease of the cartilage)

30-39:

n/a

40-49:

  1. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  2. Bone pain
  3. Dependence
  4. Drug addiction
  5. Drug dependence
  6. Dyspnoea (difficult or laboured respiration)
  7. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

50-59:

  1. Abnormal faeces (abnormal stool)
  2. Therapeutic response unexpected

60+:

  1. Glossodynia (a burning or painful sensation in the tongue)
  2. Muscle spasms (muscle contraction)
  3. Bedridden
  4. Carotid artery stenosis (narrowing of carotid artery)
  5. Cerebral infarction (less blood supply to brain resulting tissue damage)
  6. Chest pain
  7. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  8. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  9. Diarrhoea
  10. Dyskinesia (abnormality or impairment of voluntary movement)

What are the existing conditions these people have? *

  1. Back Pain: 2 people, 16.67%
  2. Vasculitis (inflammation of a blood vessel or blood vessels): 1 person, 8.33%
  3. Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 1 person, 8.33%
  4. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 1 person, 8.33%
  5. Stress And Anxiety: 1 person, 8.33%
  6. Nasopharyngitis (inflammation of the nasopharynx): 1 person, 8.33%
  7. Leukocytoclastic Vasculitis (inflammation of small blood vessels (usually post-capillary venules in the dermis), characterized by palpable purpura): 1 person, 8.33%
  8. High Blood Pressure: 1 person, 8.33%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 8.33%
  10. Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Naprosyn and Halcion:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Naprosyn:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Halcion:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Naprosyn and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Halcion and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on naproxen and triazolam (the active ingredients of Naprosyn and Halcion, respectively), and Naprosyn and Halcion (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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