Naprosyn and Plendil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Naprosyn (naproxen) and Plendil (felodipine). Common drug interactions include constipation among females and injury among males.

The phase IV clinical study analyzes what interactions people have when they take Naprosyn and Plendil. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Naprosyn?

Naprosyn has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 16,738 Naprosyn users. Check the latest studies of Naprosyn.

What is Plendil?

Plendil has active ingredients of felodipine. It is often used in high blood pressure. eHealthMe is studying from 4,990 Plendil users. Check the latest studies of Plendil.

On Jul, 15, 2026

36 people who take Naprosyn and Plendil together, and have interactions are studied.

What are the common drug interactions of Naprosyn and Plendil, by gender? *:

female:

Constipation
Dyspepsia (indigestion)
Dyspnoea (difficult or laboured respiration)
Dyspnoea exertional (breathlessness or shortness of breath)
Hypoxia (low oxygen in tissues)
Interstitial lung disease
Lacrimation increased
Nasal obstruction (blockage of nose)
Nasal turbinate hypertrophy (nasal turbinates become enlarged)
Oedema (fluid collection in tissue)

male:

Injury
Abscess (pus)
Decreased interest
Dyslipidaemia (abnormal amount of lipids)
Dyspnoea (difficult or laboured respiration)
Ejection fraction decreased (systolic heart failure)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Herpes zoster
Hyperplasia (enlargement of an organ or tissue)
Interstitial lung disease

What are the common drug interactions of Naprosyn and Plendil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Atelectasis (partial or complete collapse of the lung)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Atrophy (wasting away of a part of the body)
Bladder cancer
Bladder mass
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Cardiac arrest
Cardiac failure congestive

30-39:

Cystitis interstitial (unknown cause characterized by bladder pain)
Kidney infection
Stomach discomfort (pain in abdomen)

40-49:

Depression
Tablet in stool

50-59:

Asthma
Blood creatinine increased
Chest discomfort
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Constipation
Dyspepsia (indigestion)
Dyspnoea (difficult or laboured respiration)
Dyspnoea exertional (breathlessness or shortness of breath)
Hypoxia (low oxygen in tissues)
Interstitial lung disease

60+:

Nausea (feeling of having an urge to vomit)
Arterial embolism (sudden interruption of blood flow to an organ or body part due to an embolus adhering to the wall of an artery blocking the flow of blood)
Peripheral ischaemia (impaired circulation to an extremity)
Pulse absent
Renal impairment (severely reduced kidney function)
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Hypotension (abnormally low blood pressure)
Lung disorder (lung disease)
Pain in limb
Productive cough

What are the existing conditions these people have? *

Bone Disorder: 18 people, 50.00%
Multiple Myeloma (cancer of the plasma cells): 10 people, 27.78%
Asthma: 3 people, 8.33%
Dyspnea (difficult or laboured breathing): 2 people, 5.56%

* Approximation only. Some reports may have incomplete information.

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