Naprosyn and Sinemet cr drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Naprosyn (naproxen) and Sinemet cr (carbidopa; levodopa). Common drug interactions include anhedonia among females and depression among males.

The phase IV clinical study analyzes what interactions people have when they take Naprosyn and Sinemet cr. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Naprosyn?

Naprosyn has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 16,738 Naprosyn users. Check the latest studies of Naprosyn.

What is Sinemet cr?

Sinemet cr has active ingredients of carbidopa; levodopa. It is often used in parkinson's disease. eHealthMe is studying from 2,852 Sinemet cr users. Check the latest studies of Sinemet cr.

On Jul, 16, 2026

16 people who take Naprosyn and Sinemet cr together, and have interactions are studied.

Naprosyn and Sinemet cr drug interactions.

What are the common drug interactions of Naprosyn and Sinemet Cr, by gender? *:

female:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bereavement reaction
Dependence
Depression
Emotional distress
Fear
Feeling guilty
Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
Pathological gambling

male:

Depression
Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
Hypomania (a mild form of mania, marked by elation and hyperactivity)
Libido increased (increased sexual urge to have sex)
Pleural effusion (water on the lungs)
Pneumonia
Pyrexia (fever)
Sleep disorder
Sweating increased (excess sweating)
Syncope (loss of consciousness with an inability to maintain postural tone)

What are the common drug interactions of Naprosyn and Sinemet Cr, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Depersonalisation
Dyspnoea (difficult or laboured respiration)
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Sweating increased (excess sweating)
Syncope (loss of consciousness with an inability to maintain postural tone)
Vomiting

50-59:

n/a

60+:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Pneumonia
Pyrexia (fever)
Sleep disorder
Social avoidant behaviour (avoiding social connection a personality disorder)
Appetite disorder (abnormal eating habits)
Asthenia (weakness)
Confusional state
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)

What are the existing conditions these people have? *

Back Pain: 7 people, 43.75%
Restless Leg Syndrome (a powerful urge to move your legs): 6 people, 37.50%
Phobia Of Flying (fear of flying): 6 people, 37.50%
Insomnia (sleeplessness): 5 people, 31.25%
Epicondylitis (tennis elbow): 5 people, 31.25%
Pain In Extremity: 4 people, 25.00%
High Blood Cholesterol: 4 people, 25.00%
High Blood Pressure: 3 people, 18.75%
Itching: 2 people, 12.50%
Constipation: 2 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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