Narcan and Diovan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Narcan (naloxone hydrochloride) and Diovan (valsartan). Common drug interactions include headache among females and rash among males.

The phase IV clinical study analyzes what interactions people have when they take Narcan and Diovan. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Narcan?

Narcan has active ingredients of naloxone hydrochloride. eHealthMe is studying from 3,687 Narcan users. Check the latest studies of Narcan.

What is Diovan?

Diovan has active ingredients of valsartan. It is often used in high blood pressure. eHealthMe is studying from 83,154 Diovan users. Check the latest studies of Diovan.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

36 people who take Narcan and Diovan together, and have interactions are studied.

What are the common drug interactions of Narcan and Diovan, by gender? *:

female:

Headache (pain in head)
Chronic kidney disease
Renal failure (kidney dysfunction)
Abdominal pain
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anaphylactic reaction (serious allergic reaction)
Angiomyolipoma (most common benign tumour of the kidney)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Asthenia (weakness)

male:

Rash
Generalised oedema (swelling all over the body)
Rash macular (small, flat red spots)
Skin hyperpigmentation (disorders affect the colour of your skin)
Skin plaque (red, scaly patches to appear on the skin)
Skin ulcer haemorrhage (bleeding skin ulcer)
Asthenia (weakness)
Contusion (a type of hematoma of tissue in which capillaries)
Mobility decreased (ability to move is reduced)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

What are the common drug interactions of Narcan and Diovan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Cardiac failure congestive
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Haemorrhage (bleeding)
Hypotension (abnormally low blood pressure)
Oedema peripheral (superficial swelling)
Renal failure chronic (long lasting kidney dysfunction)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Unresponsive to stimuli

30-39:

Arthralgia (joint pain)
Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
Generalised oedema (swelling all over the body)
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Oedema peripheral (superficial swelling)
Pain
Petechiae (a small red or purple spot caused by bleeding into the skin)
Pigmentation disorder (disturbances of human skin colour)
Purpura (purplish discoloration of the skin)
Rash

40-49:

Coma (state of unconsciousness lasting more than six hours)
Confusional state
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dysuria (painful or difficult urination)
Hyperglycaemia (high blood sugar)
Hypotension (abnormally low blood pressure)
Metabolic syndrome (a combination of the medical disorders that, when occurring together, increase the risk of developing cardiovascular disease)
Rash
Renal failure (kidney dysfunction)

50-59:

Headache (pain in head)
Hepatic cyst
Hepatic steatosis (fatty liver disease)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Hyperglycaemia (high blood sugar)
Hyperlipidaemia (presence of excess lipids in the blood)
Hypersensitivity
Hypopnoea (decrease in the breathing rate)
Impaired healing
Injury

60+:

Fall
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Renal failure (kidney dysfunction)
Acute respiratory failure
Arthralgia (joint pain)
Back disorder
Blood carbon dioxide decreased
Blood glucose increased
Blood pressure decreased

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 25.00%
Nuclear Magnetic Resonance Imaging Brain: 7 people, 19.44%
Pain: 6 people, 16.67%
Osteoporosis (bones weak and more likely to break): 6 people, 16.67%
Diabetes: 4 people, 11.11%
Viral Infection: 3 people, 8.33%
Inflammation: 3 people, 8.33%
Bacterial Infection: 3 people, 8.33%
Hiv Infection: 3 people, 8.33%
Hypersensitivity: 3 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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