Natpara and Ergocalciferol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Natpara (parathyroid hormone) and Ergocalciferol (ergocalciferol). Common drug interactions include headache among females and hypocalcaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Natpara and Ergocalciferol. It is created by eHealthMe based on reports of 58 people who take the same drugs from the FDA, and is updated regularly.

What is Natpara?

Natpara has active ingredients of parathyroid hormone. eHealthMe is studying from 4,488 Natpara users. Check the latest studies of Natpara.

What is Ergocalciferol?

Ergocalciferol has active ingredients of ergocalciferol. It is often used in rickets. eHealthMe is studying from 32,652 Ergocalciferol users. Check the latest studies of Ergocalciferol.



On Jul, 20, 2026

58 people who take Natpara and Ergocalciferol together, and have interactions are studied.

Natpara and Ergocalciferol drug interactions.

What are the common drug interactions of Natpara and Ergocalciferol, by gender? *:

female:

  1. Headache (pain in head)
  2. Hypoparathyroidism (inadequate secretion of parathyroid hormone resulting in abnormally low levels of calcium in the blood)
  3. Nephrolithiasis (calculi in the kidneys)
  4. Muscle spasms (muscle contraction)
  5. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  6. Hypoaesthesia (reduced sense of touch or sensation)
  7. Blood parathyroid hormone decreased
  8. Hospitalisation
  9. Hydronephrosis (water inside the kidney)
  10. Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract)

male:

  1. Hypocalcaemia (levels of calcium in blood serum are abnormally low)
  2. Fatigue (feeling of tiredness)
  3. Malaise (a feeling of general discomfort or uneasiness)
  4. Pain
  5. Renal disorder (kidney disease)

What are the common drug interactions of Natpara and Ergocalciferol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Blood calcium decreased
  2. Hypoaesthesia (reduced sense of touch or sensation)
  3. Muscle spasms (muscle contraction)
  4. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

40-49:

  1. Malaise (a feeling of general discomfort or uneasiness)
  2. Injection site swelling
  3. Hypocalcaemia (levels of calcium in blood serum are abnormally low)
  4. Blood parathyroid hormone decreased
  5. Thyroid cancer
  6. Dysgeusia (disorder of the sense of taste)
  7. Insomnia (sleeplessness)
  8. Vomiting
  9. Weight increased
  10. Fatigue (feeling of tiredness)

50-59:

  1. Hypocalcaemia (levels of calcium in blood serum are abnormally low)
  2. Quality of life decreased
  3. Blood calcium decreased
  4. Hospitalisation
  5. Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
  6. Calcium deficiency (lack of calcium)
  7. Metastases to lung (cancer spreads to lung)
  8. Metastases to lymph nodes (cancer spreads to lymph node)
  9. Vitamin b12 deficiency

60+:

n/a

What are the existing conditions these people have? *

  1. Hypoparathyroidism (inadequate secretion of parathyroid hormone resulting in abnormally low levels of calcium in the blood): 25 people, 43.10%
  2. Hypocalcaemia (levels of calcium in blood serum are abnormally low): 16 people, 27.59%
  3. Post Procedural Hypothyroidism: 4 people, 6.90%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Natpara and Ergocalciferol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Natpara:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ergocalciferol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Natpara and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ergocalciferol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on parathyroid hormone and ergocalciferol (the active ingredients of Natpara and Ergocalciferol, respectively), and Natpara and Ergocalciferol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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