Neulasta and Actigall drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Neulasta (pegfilgrastim) and Actigall (ursodiol). Common drug interactions include abdominal pain upper among females and hepatobiliary disease among males.

The phase IV clinical study analyzes what interactions people have when they take Neulasta and Actigall. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Neulasta?

Neulasta has active ingredients of pegfilgrastim. It is often used in agranulocytosis. eHealthMe is studying from 92,286 Neulasta users. Check the latest studies of Neulasta.

What is Actigall?

Actigall has active ingredients of ursodiol. It is often used in gallstones. eHealthMe is studying from 2,162 Actigall users. Check the latest studies of Actigall.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

13 people who take Neulasta and Actigall together, and have interactions are studied.

Neulasta and Actigall drug interactions.

What are the common drug interactions of Neulasta and Actigall, by gender? *:

female:

Abdominal pain upper
Pyrexia (fever)

male:

Hepatobiliary disease (diseases affect the liver and/or biliary tract)
Febrile neutropenia (fever with reduced white blood cells)
Deafness
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Neuropathy peripheral (surface nerve damage)
Platelet count decreased
Sepsis (a severe blood infection that can lead to organ failure and death)
Thrombocytopenia (decrease of platelets in blood)
Thrombotic thrombocytopenic purpura (a rare blood disorder characterized by clotting in small blood vessels of the body)
Weight decreased

What are the common drug interactions of Neulasta and Actigall, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Hepatobiliary disease (diseases affect the liver and/or biliary tract)
Venoocclusive liver disease (small veins in the liver are obstructed)
Weight decreased

20-29:

n/a

30-39:

n/a

40-49:

Febrile neutropenia (fever with reduced white blood cells)
Sepsis (a severe blood infection that can lead to organ failure and death)

50-59:

Deafness
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Neuropathy peripheral (surface nerve damage)
Platelet count decreased
Pyrexia (fever)
Thrombocytopenia (decrease of platelets in blood)
Abdominal pain upper
Alopecia (absence of hair from areas of the body)
Ascites (accumulation of fluid in the abdominal cavity)
Blood albumin decreased

60+:

Febrile neutropenia (fever with reduced white blood cells)
Lung infection
Pneumonia
Syncope (loss of consciousness with an inability to maintain postural tone)
Vomiting
Thrombotic thrombocytopenic purpura (a rare blood disorder characterized by clotting in small blood vessels of the body)

What are the existing conditions these people have? *

Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 7 people, 53.85%
Nausea (feeling of having an urge to vomit): 3 people, 23.08%
Richter's Syndrome (hairy cell cancer changes in fast growing b cell cancer tumour): 2 people, 15.38%
Nausea And Vomiting: 2 people, 15.38%
Colon Cancer: 2 people, 15.38%
Insomnia (sleeplessness): 1 person, 7.69%
Indigestion: 1 person, 7.69%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 7.69%
Hyperbilirubinaemia (excess of bilirubin in the blood): 1 person, 7.69%
High Blood Pressure: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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