Neulasta and Bendeka drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Neulasta (pegfilgrastim) and Bendeka (bendamustine hydrochloride). Common drug interactions include dizziness among females and blood pressure decreased among males.
The phase IV clinical study analyzes what interactions people have when they take Neulasta and Bendeka. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.
What is Neulasta?
Neulasta has active ingredients of pegfilgrastim. It is often used in agranulocytosis. eHealthMe is studying from 92,286 Neulasta users. Check the latest studies of Neulasta.
What is Bendeka?
Bendeka has active ingredients of bendamustine hydrochloride. eHealthMe is studying from 591 Bendeka users. Check the latest studies of Bendeka.
32 people who take Neulasta and Bendeka together, and have interactions are studied.

What are the common drug interactions of Neulasta and Bendeka, by gender? *:
female:
- Dizziness
- Abdominal pain
- Blood pressure decreased
- Dysarthria (speech disorder)
- Incoherent (talking in a confused and unclear way)
- Nausea (feeling of having an urge to vomit)
- Pupil fixed
- Respiratory rate decreased (less breathing rate/min)
- Vomiting
- Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
male:
- Blood pressure decreased
- Drug ineffective
- Insomnia (sleeplessness)
- Lymphocyte count decreased
- Mean cell haemoglobin increased (more than normal haemoglobin per red blood cell in a sample of blood)
- Mean cell volume increased (more than normal average red blood cell volume)
- Platelet count decreased
- Rash
- Rash pruritic (redness with itching)
- Red blood cell count decreased
What are the common drug interactions of Neulasta and Bendeka, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Application site pain
- Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
60+:
- Blood pressure decreased
- Drug ineffective
- Insomnia (sleeplessness)
- Lymphocyte count decreased
- Mean cell haemoglobin increased (more than normal haemoglobin per red blood cell in a sample of blood)
- Mean cell volume increased (more than normal average red blood cell volume)
- Platelet count decreased
- Rash
- Rash pruritic (redness with itching)
- Red blood cell count decreased
What are the existing conditions these people have? *
- Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 8 people, 25.00%
- Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 6 people, 18.75%
- Waldenstrom's Macroglobulinaemia (cancer affects small lymphocytes (white blood cells)): 5 people, 15.62%
- Lymphoma (cancer that begins in immune system cells): 3 people, 9.38%
- Burkitt Lymphoma (cancer of the lymphatic system): 2 people, 6.25%
- B-Cell Small Lymphocytic Lymphoma (blood cancer affecting b cells): 2 people, 6.25%
* Approximation only. Some reports may have incomplete information.
Do you take Neulasta and Bendeka?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Neulasta and Bendeka:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Neulasta:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Bendeka:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Neulasta and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Bendeka and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Khan A, Yasin Z, "Hyperleukocytosis Caused By Neulasta Complicated By Leukostasis Versus Asymptomatic Uncomplicated Hyperleukocytosis In AML. Two Cases and When To Leukapherese.", Am Soc Hematology, 2017 Jan .
- Khan A, Yasin Z, "Hyperleukocytosis Caused By Neulasta Complicated By Leukostasis Versus Asymptomatic Uncomplicated Hyperleukocytosis In AML. Two Cases and When To Leukapherese.", Am Soc Hematology, 2017 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on pegfilgrastim and bendamustine hydrochloride (the active ingredients of Neulasta and Bendeka, respectively), and Neulasta and Bendeka (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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