Neulasta and Nplate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Neulasta (pegfilgrastim) and Nplate (romiplostim). Common drug interactions include lymphoma among females and myelodysplastic syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Neulasta and Nplate. It is created by eHealthMe based on reports of 75 people who take the same drugs from the FDA, and is updated regularly.

What is Neulasta?

Neulasta has active ingredients of pegfilgrastim. It is often used in agranulocytosis. eHealthMe is studying from 92,286 Neulasta users. Check the latest studies of Neulasta.

What is Nplate?

Nplate has active ingredients of romiplostim. It is often used in idiopathic thrombocytopenic purpura (itp). eHealthMe is studying from 17,850 Nplate users. Check the latest studies of Nplate.

On Jul, 10, 2026

75 people who take Neulasta and Nplate together, and have interactions are studied.

What are the common drug interactions of Neulasta and Nplate, by gender? *:

female:

Lymphoma (cancer that begins in immune system cells)
Bone pain
Injection site discolouration
Death
Drug ineffective
Abscess fungal (pus produced by a fungal infection)
Candidiasis (candidiasis or thrush is a fungal infection)
Enterococcal infection
Haematuria (presence of blood in urine)
Hepatic neoplasm malignant (liver cancer)

male:

Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
Neoplasm malignant (cancer tumour)
Jugular vein thrombosis (clot in jugular vein)
Myelitis (infection or the inflammation of white matter or gray matter of spinal cord which is a part of central nervous system)
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Anaemia (lack of blood)
Benign prostatic hyperplasia (benign enlargement of the prostate)
Bone marrow failure
Enterocolitis infectious

What are the common drug interactions of Neulasta and Nplate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Nausea (feeling of having an urge to vomit)
Arthralgia (joint pain)
Burning sensation
Oedema peripheral (superficial swelling)
Pulmonary embolism (blockage of the main artery of the lung)
Constipation
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Anxiety
Asthenia (weakness)
Back pain

50-59:

Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
Bone pain
Injection site discolouration
Abscess fungal (pus produced by a fungal infection)
Candidiasis (candidiasis or thrush is a fungal infection)
Enterococcal infection
Haematuria (presence of blood in urine)
Hepatic neoplasm malignant (liver cancer)
Hyperglycaemia (high blood sugar)
Hypoaesthesia (reduced sense of touch or sensation)

60+:

Neoplasm malignant (cancer tumour)
Death
Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Anaemia (lack of blood)
Asthenia (weakness)
Benign prostatic hyperplasia (benign enlargement of the prostate)
Bone marrow failure
Enterocolitis infectious

What are the existing conditions these people have? *

Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 30 people, 40.00%
Anaemia (lack of blood): 6 people, 8.00%
Anaemia Of Malignant Disease: 4 people, 5.33%

* Approximation only. Some reports may have incomplete information.

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