Neulasta and Tarceva drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Neulasta (pegfilgrastim) and Tarceva (erlotinib hydrochloride). Common drug interactions include dyspnoea among females and ejection fraction decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Neulasta and Tarceva. It is created by eHealthMe based on reports of 76 people who take the same drugs from the FDA, and is updated regularly.

What is Neulasta?

Neulasta has active ingredients of pegfilgrastim. It is often used in agranulocytosis. eHealthMe is studying from 92,286 Neulasta users. Check the latest studies of Neulasta.

What is Tarceva?

Tarceva has active ingredients of erlotinib hydrochloride. It is often used in lung cancer. eHealthMe is studying from 31,036 Tarceva users. Check the latest studies of Tarceva.

On Aug, 07, 2026

76 people who take Neulasta and Tarceva together, and have interactions are studied.

What are the common drug interactions of Neulasta and Tarceva, by gender? *:

female:

Dyspnoea (difficult or laboured respiration)
Pain
Arthralgia (joint pain)
Diarrhoea
Fall
Malaise (a feeling of general discomfort or uneasiness)
Pleural effusion (water on the lungs)
Productive cough
Rash
Ascites (accumulation of fluid in the abdominal cavity)

male:

Ejection fraction decreased (systolic heart failure)
Death
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Depression
Fatigue (feeling of tiredness)
Injury
Thrombocytopenia (decrease of platelets in blood)
Toothache (tooth pain)
Abscess (pus)
Back pain

What are the common drug interactions of Neulasta and Tarceva, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Death

30-39:

Abdominal rigidity
Anaemia (lack of blood)
Anxiety
Arthralgia (joint pain)
Asthenia (weakness)
Back pain
Cough
Death
Drug ineffective
Fall

40-49:

Pleural effusion (water on the lungs)
Abdominal discomfort
Anaemia (lack of blood)
Anxiety
Arthralgia (joint pain)
Ascites (accumulation of fluid in the abdominal cavity)
Aspartate aminotransferase increased
Back pain
Blood alkaline phosphatase increased
Blood calcium decreased

50-59:

Platelet count decreased
Abscess (pus)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Back pain
Bone disorder
Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
Depressed mood
Depression
Hydronephrosis (water inside the kidney)
Hyperlipidaemia (presence of excess lipids in the blood)

60+:

Ejection fraction decreased (systolic heart failure)
Dilatation ventricular
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Arthralgia (joint pain)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Metastases to bone marrow (cancer spreads to bone marrow)
Metastases to spine (cancer spreads to spine)

What are the existing conditions these people have? *

Lung Neoplasm Malignant (cancer tumour of lung): 19 people, 25.00%
Pain: 8 people, 10.53%
Pancreatic Carcinoma (pancreatic cancer): 7 people, 9.21%
Lung Adenocarcinoma Metastatic (a form of non-small cell lung cancer spreads to other part): 5 people, 6.58%
Breast Cancer Metastatic: 5 people, 6.58%
Lung Cancer - Non-Small Cell (lung cancer): 4 people, 5.26%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 5.26%
Anaemia (lack of blood): 4 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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