Neupro and Oxycodone and acetaminophen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Neupro (rotigotine) and Oxycodone and acetaminophen (acetaminophen; oxycodone hydrochloride). Common drug interactions include memory impairment among females and fall among males.

The phase IV clinical study analyzes what interactions people have when they take Neupro and Oxycodone and acetaminophen. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Neupro?

Neupro has active ingredients of rotigotine. It is often used in parkinson's disease. eHealthMe is studying from 11,393 Neupro users. Check the latest studies of Neupro.

What is Oxycodone and acetaminophen?

Oxycodone and acetaminophen has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 14,467 Oxycodone and acetaminophen users. Check the latest studies of Oxycodone and acetaminophen.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 04, 2026

27 people who take Neupro and Oxycodone and acetaminophen together, and have interactions are studied.

Neupro and Oxycodone and acetaminophen drug interactions.

What are the common drug interactions of Neupro and Oxycodone And Acetaminophen, by gender? *:

female:

  1. Memory impairment
  2. Nausea (feeling of having an urge to vomit)
  3. Skin irritation
  4. Drug ineffective
  5. Neuropathy peripheral (surface nerve damage)
  6. Pneumonia
  7. Application site erythema (redness of the skin at application site)
  8. Application site pruritus (application site severe itching of the skin)
  9. Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
  10. Heart rate irregular

male:

  1. Fall
  2. Cardiac arrest
  3. Application site irritation
  4. Application site pruritus (application site severe itching of the skin)
  5. Asthenia (weakness)
  6. Atrioventricular block (heart block)
  7. Bladder disorder
  8. Device dislocation
  9. Drug ineffective
  10. Dysstasia (difficulty in standing)

What are the common drug interactions of Neupro and Oxycodone And Acetaminophen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Drug ineffective
  2. Fall
  3. Ankle fracture
  4. Application site irritation
  5. Bladder disorder
  6. Cardiac arrest
  7. Device dislocation
  8. Dyskinesia (abnormality or impairment of voluntary movement)
  9. Erythema (redness of the skin)
  10. Hip fracture

What are the existing conditions these people have? *

  1. Drowsiness: 8 people, 29.63%
  2. Hypersensitivity: 5 people, 18.52%
  3. Restless Leg Syndrome (a powerful urge to move your legs): 4 people, 14.81%
  4. Constipation: 3 people, 11.11%
  5. Itching: 3 people, 11.11%
  6. Stress And Anxiety: 3 people, 11.11%
  7. Depression: 3 people, 11.11%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 11.11%
  9. Cough: 2 people, 7.41%
  10. Discomfort: 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

Do you take Neupro and Oxycodone and acetaminophen?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Neupro and Oxycodone and acetaminophen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Neupro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Oxycodone and acetaminophen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Neupro and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Oxycodone and acetaminophen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on rotigotine and acetaminophen; oxycodone hydrochloride (the active ingredients of Neupro and Oxycodone and acetaminophen, respectively), and Neupro and Oxycodone and acetaminophen (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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