Nexavar and Codeine sulfate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nexavar (sorafenib tosylate) and Codeine sulfate (codeine sulfate). Common drug interactions include diarrhoea among females and palmar-plantar erythrodysaesthesia syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Nexavar and Codeine sulfate. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Nexavar?

Nexavar has active ingredients of sorafenib tosylate. It is often used in hepatocellular carcinoma. eHealthMe is studying from 23,250 Nexavar users. Check the latest studies of Nexavar.

What is Codeine sulfate?

Codeine sulfate has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 4,510 Codeine sulfate users. Check the latest studies of Codeine sulfate.

On Aug, 04, 2026

23 people who take Nexavar and Codeine sulfate together, and have interactions are studied.

Nexavar and Codeine sulfate drug interactions.

What are the common drug interactions of Nexavar and Codeine Sulfate, by gender? *:

female:

Diarrhoea
Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Platelet count decreased
Hypertension (high blood pressure)
Radiation pneumonitis (inflammation of lung due to radiation)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Pneumonia
Decreased appetite
Arrhythmia (irregular heartbeat)

male:

Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
Diarrhoea
Pancreatic disorder
Platelet count increased
Blood amylase increased
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
Lipase increased
Cerebral haemorrhage (bleeding within the brain)
Respiratory failure (inadequate gas exchange by the respiratory system)
White blood cell count decreased

What are the common drug interactions of Nexavar and Codeine Sulfate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
Hypertension (high blood pressure)
Diarrhoea
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Alopecia (absence of hair from areas of the body)
Cerebral haemorrhage (bleeding within the brain)
Radiation pneumonitis (inflammation of lung due to radiation)
Blood amylase increased
Lipase increased
Abdominal distension

60+:

Diarrhoea
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Decreased appetite
Blood alkaline phosphatase increased
Blood lactate dehydrogenase increased
Eosinophil count increased
Gastritis (inflammation of stomach)
Herpes zoster
Proteinuria (presence of protein in the urine)
Gastroenteritis radiation (radiation induced inflammation of stomach and intestine)

What are the existing conditions these people have? *

Hepatic Neoplasm Malignant (liver cancer): 11 people, 47.83%
Renal Cell Carcinoma (a kidney cancer): 10 people, 43.48%
Constipation: 3 people, 13.04%
Nausea (feeling of having an urge to vomit): 2 people, 8.70%
Diarrhea: 2 people, 8.70%
Cough: 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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