Niaspan and Propulsid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Niaspan (niacin) and Propulsid (cisapride monohydrate). Common drug interactions include maculopathy among females and flushing among males.

The phase IV clinical study analyzes what interactions people have when they take Niaspan and Propulsid. It is created by eHealthMe based on reports of 49 people who take the same drugs from the FDA, and is updated regularly.

What is Niaspan?

Niaspan has active ingredients of niacin. It is often used in high blood cholesterol. eHealthMe is studying from 45,453 Niaspan users. Check the latest studies of Niaspan.

What is Propulsid?

Propulsid has active ingredients of cisapride monohydrate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 8,130 Propulsid users. Check the latest studies of Propulsid.

On Jul, 20, 2026

49 people who take Niaspan and Propulsid together, and have interactions are studied.

Niaspan and Propulsid drug interactions.

What are the common drug interactions of Niaspan and Propulsid, by gender? *:

female:

Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest)
Memory impairment
Metamorphopsia (a type of distorted vision in which a grid of straight lines appears wavy and parts of the grid may appear blank)
Mucosal inflammation (infection of mucous membrane)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Myalgia (muscle pain)
Nasopharyngitis (inflammation of the nasopharynx)
Oesophageal achalasia (difficulty swallowing, food sticking in the oesophagus)
Pain in jaw
Pain of skin

male:

Flushing (the warm, red condition of human skin)
Abdominal pain
Alopecia (absence of hair from areas of the body)
Appetite decreased (decreased appetite occurs when you have a reduced desire to eat)
Arrhythmia (irregular heartbeat)
Atrophy (wasting away of a part of the body)
Back disorder
Blood testosterone decreased
Bradycardia (abnormally slow heart action)
Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)

What are the common drug interactions of Niaspan and Propulsid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Depression
Fatigue (feeling of tiredness)
Influenza
Oedema lower limb (fluid collection in tissue of lower leg)
Oedema upper limb (swelling of arm)
Vision blurred
Abdominal distension
Abdominal pain
Abdominal pain upper
Affect lability (emotional incontinence)

50-59:

Pruritus (severe itching of the skin)
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Malaise (a feeling of general discomfort or uneasiness)
Sudden onset of sleep
Chronic kidney disease
Colitis ulcerative (inflammation of colon with ulcer)
Drug maladministration

60+:

Dysphagia (a condition in which swallowing is difficult or painful)
Tardive dyskinesia (a disorder that involves involuntary movements)
Sensation of foreign body
Tinnitus (a ringing in the ears)
Balance disorder
Blindness
Dizziness
Ear pain
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Headache (pain in head)

* Approximation only. Some reports may have incomplete information.

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