Nicotinamide and Lidoderm drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nicotinamide (niacin and niacinamide (vitamin b3)) and Lidoderm (lidocaine). Common drug interactions include contusion among females.

The phase IV clinical study analyzes what interactions people have when they take Nicotinamide and Lidoderm. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Nicotinamide?

Nicotinamide has active ingredients of niacin and niacinamide (vitamin b3). eHealthMe is studying from 1,991 Nicotinamide users. Check the latest studies of Nicotinamide.

What is Lidoderm?

Lidoderm has active ingredients of lidocaine. It is often used in pain. eHealthMe is studying from 10,524 Lidoderm users. Check the latest studies of Lidoderm.



On Jul, 15, 2026

14 people who take Nicotinamide and Lidoderm together, and have interactions are studied.

Nicotinamide and Lidoderm drug interactions.

What are the common drug interactions of Nicotinamide and Lidoderm, by gender? *:

female:

  1. Contusion (a type of hematoma of tissue in which capillaries)
  2. Headache (pain in head)
  3. Cellulitis (infection under the skin)
  4. Cerumen impaction
  5. Cough
  6. Diarrhoea
  7. Discomfort
  8. Dry mouth
  9. Dysgeusia (disorder of the sense of taste)
  10. Dysphonia (speech disorder attributable to a disorder of phonation)

male:

n/a

What are the common drug interactions of Nicotinamide and Lidoderm, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Allergy to arthropod sting
  2. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  3. Contusion (a type of hematoma of tissue in which capillaries)
  4. Discomfort
  5. Dry mouth
  6. Dysgeusia (disorder of the sense of taste)
  7. Dysphagia (a condition in which swallowing is difficult or painful)
  8. Erythema (redness of the skin)
  9. Headache (pain in head)
  10. Muscle tightness

60+:

  1. Oedema (fluid collection in tissue)
  2. Pain in extremity
  3. Dyspnoea (difficult or laboured respiration)
  4. Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
  5. Headache (pain in head)
  6. Laryngitis (inflammation of the larynx)
  7. Loss of proprioception (loss of senses of body and parts)
  8. Nasal oedema (fluid collection in nose)
  9. Nasal septum deviation (deviated nasal septum)
  10. Phlebitis superficial (inflammation of the walls of a vein-superficial)

What are the existing conditions these people have? *

  1. Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 10 people, 71.43%
  2. Essential Thrombocythaemia (chronic blood cancer): 7 people, 50.00%
  3. Hyperlipidaemia (presence of excess lipids in the blood): 5 people, 35.71%
  4. Haemorrhoids (a swollen vein or group of veins in the region of the anus): 5 people, 35.71%
  5. Dry Eyes (lack of adequate tears): 5 people, 35.71%
  6. Upper Respiratory Tract Infection: 5 people, 35.71%
  7. Insomnia (sleeplessness): 5 people, 35.71%
  8. Cough: 5 people, 35.71%
  9. Constipation: 5 people, 35.71%
  10. Mouth Ulcers: 5 people, 35.71%

* Approximation only. Some reports may have incomplete information.

Do you take Nicotinamide and Lidoderm?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Nicotinamide and Lidoderm:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nicotinamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lidoderm:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nicotinamide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lidoderm and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on niacin and niacinamide (vitamin b3) and lidocaine (the active ingredients of Nicotinamide and Lidoderm, respectively), and Nicotinamide and Lidoderm (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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