Nifedipine and Cortef drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nifedipine (nifedipine) and Cortef (hydrocortisone). Common drug interactions include cardiac flutter among females and peripheral ischaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Nifedipine and Cortef. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Nifedipine?

Nifedipine has active ingredients of nifedipine. It is often used in high blood pressure. eHealthMe is studying from 53,459 Nifedipine users. Check the latest studies of Nifedipine.

What is Cortef?

Cortef has active ingredients of hydrocortisone. It is often used in addison's disease. eHealthMe is studying from 4,254 Cortef users. Check the latest studies of Cortef.

On Jul, 13, 2026

15 people who take Nifedipine and Cortef together, and have interactions are studied.

Nifedipine and Cortef drug interactions.

What are the common drug interactions of Nifedipine and Cortef, by gender? *:

female:

Cardiac flutter (abnormal heart rhythm)
Cardioversion
Catheter site haemorrhage (bleeding at catheter site)
Decreased appetite
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Gallbladder disorder
Heart rate increased
Hyperthyroidism (over activity of the thyroid gland)

male:

Peripheral ischaemia (impaired circulation to an extremity)
B-cell lymphoma (blood cancer affecting b cells)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Lymphoproliferative disorder (a medical condition in which the immune system makes too many white blood cells)
Renal failure acute (rapid kidney dysfunction)

What are the common drug interactions of Nifedipine and Cortef, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

B-cell lymphoma (blood cancer affecting b cells)
Bundle branch block (disruption in the normal flow of electrical pulses that drive the heart beat)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Confusional state
Dizziness
Lobar pneumonia (a form of pneumonia that affects a large and continuous area of the lobe of a lung)
Lymphoproliferative disorder (a medical condition in which the immune system makes too many white blood cells)
Renal failure acute (rapid kidney dysfunction)
Respiratory failure (inadequate gas exchange by the respiratory system)
Septic shock (shock due to blood infection)

50-59:

Confusional state
Decreased appetite
Diarrhoea
Dizziness
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Gallbladder disorder
Heart rate increased
Hyperthyroidism (over activity of the thyroid gland)
Hypotension (abnormally low blood pressure)

60+:

Peripheral ischaemia (impaired circulation to an extremity)
Erythema (redness of the skin)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Pruritus (severe itching of the skin)
Rash generalised (rash on most of body parts)

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 26.67%
Pain: 3 people, 20.00%
Hypersensitivity: 2 people, 13.33%
Migraine (headache): 2 people, 13.33%
Vitamin D Decreased: 1 person, 6.67%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 1 person, 6.67%
Glucose Tolerance Impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis): 1 person, 6.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 6.67%
Fungal Infection: 1 person, 6.67%
Food Allergy: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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